Gu X - Search Results

1

Novel oral compound Z526 mitigates cancer-associated cachexia via intervening NF-κB signaling and oxidative stress.

Gu X, Lu S, Xu S, Li Y, Fan M, Lin G, Liu Y, Zhao Y, Zhao W, Liu X, Dong X, Zhang X. Gu X, et al. Genes Dis. 2024 Apr 8;12(2):101292. doi: 10.1016/j.gendis.2024.101292. eCollection 2025 Mar. Genes Dis. 2024. PMID: 39759112 Free PMC article.

2

Compound Z526 alleviates chemotherapy-induced cachectic muscle loss by ameliorating oxidative stress-driven protein metabolic imbalance and apoptosis.

Gu X, Lu S, Fan M, Xu S, Lin G, Zhao Y, Zhao W, Liu X, Dong X, Zhang X. Gu X, et al. Eur J Pharmacol. 2024 Jul 5;974:176538. doi: 10.1016/j.ejphar.2024.176538. Epub 2024 Mar 27. Eur J Pharmacol. 2024. PMID: 38552940

3

Carnosol and its analogues attenuate muscle atrophy and fat lipolysis induced by cancer cachexia.

Lu S, Li Y, Shen Q, Zhang W, Gu X, Ma M, Li Y, Zhang L, Liu X, Zhang X. Lu S, et al. Among authors: gu x. J Cachexia Sarcopenia Muscle. 2021 Jun;12(3):779-795. doi: 10.1002/jcsm.12710. Epub 2021 May 5. J Cachexia Sarcopenia Muscle. 2021. PMID: 33951335 Free PMC article.

4

Cancer-derived exosome miRNAs induce skeletal muscle wasting by Bcl-2-mediated apoptosis in colon cancer cachexia.

Miao C, Zhang W, Feng L, Gu X, Shen Q, Lu S, Fan M, Li Y, Guo X, Ma Y, Liu X, Wang H, Zhang X. Miao C, et al. Among authors: gu x. Mol Ther Nucleic Acids. 2021 Apr 24;24:923-938. doi: 10.1016/j.omtn.2021.04.015. eCollection 2021 Jun 4. Mol Ther Nucleic Acids. 2021. PMID: 34094711 Free PMC article.

5

Bile acid metabolism dysregulation associates with cancer cachexia: roles of liver and gut microbiome.

Feng L, Zhang W, Shen Q, Miao C, Chen L, Li Y, Gu X, Fan M, Ma Y, Wang H, Liu X, Zhang X. Feng L, et al. Among authors: gu x. J Cachexia Sarcopenia Muscle. 2021 Dec;12(6):1553-1569. doi: 10.1002/jcsm.12798. Epub 2021 Sep 28. J Cachexia Sarcopenia Muscle. 2021. PMID: 34585527 Free PMC article.

6

The critical role of STAT3 in biogenesis of tumor-derived exosomes with potency of inducing cancer cachexia in vitro and in vivo.

Fan M, Sun W, Gu X, Lu S, Shen Q, Liu X, Zhang X. Fan M, et al. Among authors: gu x. Oncogene. 2022 Feb;41(7):1050-1062. doi: 10.1038/s41388-021-02151-3. Epub 2022 Jan 16. Oncogene. 2022. PMID: 35034093

7

Atractylenolide I ameliorates cancer cachexia through inhibiting biogenesis of IL-6 and tumour-derived extracellular vesicles.

Fan M, Gu X, Zhang W, Shen Q, Zhang R, Fang Q, Wang Y, Guo X, Zhang X, Liu X. Fan M, et al. Among authors: gu x. J Cachexia Sarcopenia Muscle. 2022 Dec;13(6):2724-2739. doi: 10.1002/jcsm.13079. Epub 2022 Sep 9. J Cachexia Sarcopenia Muscle. 2022. PMID: 36085573 Free PMC article.

8

miR-126-5p affects the chemosensitivity of colorectal cancer cells by regulating SPRED1, ERK1/2 pathway and apoptosis.

Xu M, Zhang G, Gu X, Zhao F, Yang Z, Zhang X. Xu M, et al. Among authors: gu x. Genes Dis. 2022 Jun 4;10(3):675-678. doi: 10.1016/j.gendis.2022.05.024. eCollection 2023 May. Genes Dis. 2022. PMID: 37396522 Free PMC article. No abstract available.

9

Carnosol analogue WK-63 alleviated cancer cachexia by inhibiting NF-κB and activating AKT pathways in muscle while inhibiting NF-κB and AMPK pathways in adipocyte.

Pan X, Zhang G, Wei K, Gu X, Dan J, Zhao Y, Liu X, Cheng C, Zhang X. Pan X, et al. Among authors: gu x. Toxicol Appl Pharmacol. 2023 Nov 15;479:116729. doi: 10.1016/j.taap.2023.116729. Epub 2023 Oct 18. Toxicol Appl Pharmacol. 2023. PMID: 37863360

10

Paeoniflorin alleviated muscle atrophy in cancer cachexia through inhibiting TLR4/NF-κB signaling and activating AKT/mTOR signaling.

Zhu Z, Li C, Gu X, Wang X, Zhang G, Fan M, Zhao Y, Liu X, Zhang X. Zhu Z, et al. Among authors: gu x. Toxicol Appl Pharmacol. 2024 Mar;484:116846. doi: 10.1016/j.taap.2024.116846. Epub 2024 Feb 6. Toxicol Appl Pharmacol. 2024. PMID: 38331105

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