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Spatial tumor immune heterogeneity facilitates subtype co-existence and therapy response in pancreatic cancer.
Klein L, Tu M, Krebs N, Urbach L, Grimm D, Latif MU, Penz F, Blandau A, Wu X, Samuel RD, Küffer S, Wegwitz F, Chan N, Aliar K, Vyas F, Kishore U, Hessmann E, Trumpp A, Espinet E, Papantonis A, Khokha R, Ellenrieder V, Grünwald BT, Singh SK. Klein L, et al. Among authors: wegwitz f. Nat Commun. 2025 Jan 6;16(1):335. doi: 10.1038/s41467-024-55330-7. Nat Commun. 2025. PMID: 39762215 Free PMC article.
A Novel AMPK Inhibitor Sensitizes Pancreatic Cancer Cells to Ferroptosis Induction.
Schneider C, Hilbert J, Genevaux F, Höfer S, Krauß L, Schicktanz F, Contreras CT, Jansari S, Papargyriou A, Richter T, Alfayomy AM, Falcomatà C, Schneeweis C, Orben F, Öllinger R, Wegwitz F, Boshnakovska A, Rehling P, Müller D, Ströbel P, Ellenrieder V, Conradi L, Hessmann E, Ghadimi M, Grade M, Wirth M, Steiger K, Rad R, Kuster B, Sippl W, Reichert M, Saur D, Schneider G. Schneider C, et al. Among authors: wegwitz f. Adv Sci (Weinh). 2024 Aug;11(31):e2307695. doi: 10.1002/advs.202307695. Epub 2024 Jun 17. Adv Sci (Weinh). 2024. PMID: 38885414 Free PMC article.
Enhancement of colorectal cancer therapy through interruption of the HSF1-HSP90 axis by p53 activation or cell cycle inhibition.
Isermann T, Schneider KL, Wegwitz F, De Oliveira T, Conradi LC, Volk V, Feuerhake F, Papke B, Stintzing S, Mundt B, Kühnel F, Moll UM, Schulz-Heddergott R. Isermann T, et al. Among authors: wegwitz f. bioRxiv [Preprint]. 2024 Feb 26:2024.02.22.581507. doi: 10.1101/2024.02.22.581507. bioRxiv. 2024. PMID: 38464125 Free PMC article. Preprint.
Identification of a ΔNp63-Dependent Basal-Like A Subtype-Specific Transcribed Enhancer Program (B-STEP) in Aggressive Pancreatic Ductal Adenocarcinoma.
Wang X, Kutschat AP, Aggrey-Fynn J, Hamdan FH, Graham RP, Wixom AQ, Souto Y, Ladigan-Badura S, Yonkus JA, Abdelrahman AM, Alva-Ruiz R, Gaedcke J, Ströbel P, Kosinsky RL, Wegwitz F, Hermann P, Truty MJ, Siveke JT, Hahn SA, Hessmann E, Johnsen SA, Najafova Z. Wang X, et al. Among authors: wegwitz f. Mol Cancer Res. 2023 Sep 1;21(9):881-891. doi: 10.1158/1541-7786.MCR-22-0916. Mol Cancer Res. 2023. PMID: 37279184 Free PMC article.
ROBO3s: a novel ROBO3 short isoform promoting breast cancer aggressiveness.
Werner M, Dyas A, Parfentev I, Schmidt GE, Mieczkowska IK, Müller-Kirschbaum LC, Müller C, Kalkhof S, Reinhardt O, Urlaub H, Alves F, Gallwas J, Prokakis E, Wegwitz F. Werner M, et al. Among authors: wegwitz f. Cell Death Dis. 2022 Sep 3;13(9):762. doi: 10.1038/s41419-022-05197-7. Cell Death Dis. 2022. PMID: 36057630 Free PMC article.
Axon guidance receptor ROBO3 modulates subtype identity and prognosis via AXL-associated inflammatory network in pancreatic cancer.
Krebs N, Klein L, Wegwitz F, Espinet E, Maurer HC, Tu M, Penz F, Küffer S, Xu X, Bohnenberger H, Cameron S, Brunner M, Neesse A, Kishore U, Hessmann E, Trumpp A, Ströbel P, Brekken RA, Ellenrieder V, Singh SK. Krebs N, et al. Among authors: wegwitz f. JCI Insight. 2022 Aug 22;7(16):e154475. doi: 10.1172/jci.insight.154475. JCI Insight. 2022. PMID: 35993361 Free PMC article.
46 results