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A generative framework for enhanced cell-type specificity in rationally designed mRNAs.
Khoroshkin M, Zinkevich A, Aristova E, Yousefi H, Lee SB, Mittmann T, Manegold K, Penzar D, Raleigh DR, Kulakovskiy IV, Goodarzi H. Khoroshkin M, et al. Among authors: goodarzi h. bioRxiv [Preprint]. 2024 Dec 31:2024.12.31.630783. doi: 10.1101/2024.12.31.630783. bioRxiv. 2024. PMID: 39803435 Free PMC article. Preprint.
Deep generative AI models analyzing circulating orphan non-coding RNAs enable detection of early-stage lung cancer.
Karimzadeh M, Momen-Roknabadi A, Cavazos TB, Fang Y, Chen NC, Multhaup M, Yen J, Ku J, Wang J, Zhao X, Murzynowski P, Wang K, Hanna R, Huang A, Corti D, Nguyen D, Lam T, Kilinc S, Arensdorf P, Chau KH, Hartwig A, Fish L, Li H, Behsaz B, Elemento O, Zou J, Hormozdiari F, Alipanahi B, Goodarzi H. Karimzadeh M, et al. Among authors: goodarzi h. Nat Commun. 2024 Nov 21;15(1):10090. doi: 10.1038/s41467-024-53851-9. Nat Commun. 2024. PMID: 39572521 Free PMC article.
The single-molecule accessibility landscape of newly replicated mammalian chromatin.
Ostrowski MS, Yang MG, McNally CP, Abdulhay NJ, Wang S, Renduchintala K, Irkliyenko I, Biran A, Chew BTL, Midha AD, Wong EV, Sandoval J, Jain IH, Groth A, Nora EP, Goodarzi H, Ramani V. Ostrowski MS, et al. Among authors: goodarzi h. Cell. 2025 Jan 9;188(1):237-252.e19. doi: 10.1016/j.cell.2024.10.039. Epub 2024 Nov 15. Cell. 2025. PMID: 39549698 Free article.
Author Correction: Systematic identification of post-transcriptional regulatory modules.
Khoroshkin M, Buyan A, Dodel M, Navickas A, Yu J, Trejo F, Doty A, Baratam R, Zhou S, Lee SB, Joshi T, Garcia K, Choi B, Miglani S, Subramanyam V, Modi H, Carpenter C, Markett D, Corces MR, Mardakheh FK, Kulakovskiy IV, Goodarzi H. Khoroshkin M, et al. Among authors: goodarzi h. Nat Commun. 2024 Oct 28;15(1):9277. doi: 10.1038/s41467-024-52903-4. Nat Commun. 2024. PMID: 39468017 Free PMC article. No abstract available.
Functional screen for mediators of onco-mRNA translation specificity.
Kovalski JR, Sarioglu G, Subramanyam V, Hernandez G, Rademaker G, Oses-Prieto JA, Slota M, Mohan N, Yiakis K, Liu I, Wen KW, Kim GE, Miglani S, Burlingame AL, Goodarzi H, Perera RM, Ruggero D. Kovalski JR, et al. Among authors: goodarzi h. bioRxiv [Preprint]. 2024 Oct 11:2024.10.10.617637. doi: 10.1101/2024.10.10.617637. bioRxiv. 2024. PMID: 39416102 Free PMC article. Preprint.
194 results