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231 results

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E-box independent chromatin recruitment turns MYOD into a transcriptional repressor.
Nicoletti C, Massenet J, Pintado-Urbanc AP, Connor LJ, Nicolau M, Sundar S, Xu M, Schmitt A, Zhang W, Fang Z, Chan TCI, Tapscott SJ, Cheung TH, Simon MD, Caputo L, Puri PL. Nicoletti C, et al. Among authors: tapscott sj. bioRxiv [Preprint]. 2024 Dec 5:2024.12.05.627024. doi: 10.1101/2024.12.05.627024. bioRxiv. 2024. PMID: 39677796 Free PMC article. Preprint.
Suspended Tissue Open Microfluidic Patterning (STOMP).
Haack AJ, Brown LG, Goldstein AJ, Mulimani P, Berthier J, Viswanathan AR, Kopyeva I, Whitten JM, Lin A, Nguyen SH, Leahy TP, Bouker EE, Padgett RM, Mazzawi NA, Tokihiro JC, Bretherton RC, Wu A, Tapscott SJ, DeForest CA, Popowics TE, Berthier E, Sniadecki NJ, Theberge AB. Haack AJ, et al. Among authors: tapscott sj. bioRxiv [Preprint]. 2024 Oct 7:2024.10.04.616662. doi: 10.1101/2024.10.04.616662. bioRxiv. 2024. PMID: 39416011 Free PMC article. Preprint.
AI driven analysis of MRI to measure health and disease progression in FSHD.
Riem L, DuCharme O, Cousins M, Feng X, Kenney A, Morris J, Tapscott SJ, Tawil R, Statland J, Shaw D, Wang L, Walker M, Lewis L, Jacobs MA, Leung DG, Friedman SD, Blemker SS. Riem L, et al. Among authors: tapscott sj. Sci Rep. 2024 Jul 5;14(1):15462. doi: 10.1038/s41598-024-65802-x. Sci Rep. 2024. PMID: 38965267 Free PMC article.
Regional and bilateral MRI and gene signatures in facioscapulohumeral dystrophy: implications for clinical trial design and mechanisms of disease progression.
Wong CJ, Friedman SD, Snider L, Bennett SR, Jones TI, Jones PL, Shaw DWW, Blemker SS, Riem L, DuCharme O, Lemmers RJFL, van der Maarel SM, Wang LH, Tawil R, Statland JM, Tapscott SJ. Wong CJ, et al. Among authors: tapscott sj. Hum Mol Genet. 2024 Apr 8;33(8):698-708. doi: 10.1093/hmg/ddae007. Hum Mol Genet. 2024. PMID: 38268317
snRNA-seq analysis in multinucleated myogenic FSHD cells identifies heterogeneous FSHD transcriptome signatures associated with embryonic-like program activation and oxidative stress-induced apoptosis.
Zheng D, Wondergem A, Kloet S, Willemsen I, Balog J, Tapscott SJ, Mahfouz A, van den Heuvel A, van der Maarel SM. Zheng D, et al. Among authors: tapscott sj. Hum Mol Genet. 2024 Jan 20;33(3):284-298. doi: 10.1093/hmg/ddad186. Hum Mol Genet. 2024. PMID: 37934801 Free PMC article.
The transcription factor DUX4 orchestrates translational reprogramming by broadly suppressing translation efficiency and promoting expression of DUX4-induced mRNAs.
Hamm DC, Paatela EM, Bennett SR, Wong CJ, Campbell AE, Wladyka CL, Smith AA, Jagannathan S, Hsieh AC, Tapscott SJ. Hamm DC, et al. Among authors: tapscott sj. PLoS Biol. 2023 Sep 25;21(9):e3002317. doi: 10.1371/journal.pbio.3002317. eCollection 2023 Sep. PLoS Biol. 2023. PMID: 37747887 Free PMC article.
DUX4 expression in cancer induces a metastable early embryonic totipotent program.
Smith AA, Nip Y, Bennett SR, Hamm DC, Lemmers RJLF, van der Vliet PJ, Setty M, van der Maarel SM, Tapscott SJ. Smith AA, et al. Among authors: tapscott sj. Cell Rep. 2023 Sep 26;42(9):113114. doi: 10.1016/j.celrep.2023.113114. Epub 2023 Sep 8. Cell Rep. 2023. PMID: 37691147 Free PMC article.
231 results