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Sterile production of interferons in the thymus affects T cell repertoire selection.
Ashby KM, Vobořil M, Salgado OC, Lee ST, Martinez RJ, O'Connor CH, Breed ER, Xuan S, Roll CR, Bachigari S, Heiland H, Stetson DB, Kotenko SV, Hogquist KA. Ashby KM, et al. Among authors: stetson db. Sci Immunol. 2024 Jul 26;9(97):eadp1139. doi: 10.1126/sciimmunol.adp1139. Epub 2024 Jul 26. Sci Immunol. 2024. PMID: 39058762
Early cellular mechanisms of type I interferon-driven susceptibility to tuberculosis.
Kotov DI, Lee OV, Fattinger SA, Langner CA, Guillen JV, Peters JM, Moon A, Burd EM, Witt KC, Stetson DB, Jaye DL, Bryson BD, Vance RE. Kotov DI, et al. Among authors: stetson db. Cell. 2023 Dec 7;186(25):5536-5553.e22. doi: 10.1016/j.cell.2023.11.002. Epub 2023 Nov 28. Cell. 2023. PMID: 38029747 Free PMC article.
Computational design of constitutively active cGAS.
Dowling QM, Volkman HE, Gray EE, Ovchinnikov S, Cambier S, Bera AK, Sankaran B, Johnson MR, Bick MJ, Kang A, Stetson DB, King NP. Dowling QM, et al. Among authors: stetson db. Nat Struct Mol Biol. 2023 Jan;30(1):72-80. doi: 10.1038/s41594-022-00862-z. Epub 2023 Jan 2. Nat Struct Mol Biol. 2023. PMID: 36593311
ADAR1 mutation causes ZBP1-dependent immunopathology.
Hubbard NW, Ames JM, Maurano M, Chu LH, Somfleth KY, Gokhale NS, Werner M, Snyder JM, Lichauco K, Savan R, Stetson DB, Oberst A. Hubbard NW, et al. Among authors: stetson db. Nature. 2022 Jul;607(7920):769-775. doi: 10.1038/s41586-022-04896-7. Epub 2022 Jul 20. Nature. 2022. PMID: 35859177 Free PMC article.
The type I interferonopathies: 10 years on.
Crow YJ, Stetson DB. Crow YJ, et al. Among authors: stetson db. Nat Rev Immunol. 2022 Aug;22(8):471-483. doi: 10.1038/s41577-021-00633-9. Epub 2021 Oct 20. Nat Rev Immunol. 2022. PMID: 34671122 Free PMC article. Review.
43 results