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Page 1
4-Substituted-2-Thiazole Amides as Viral Replication Inhibitors of Alphaviruses.
Garzan A, Ahmed SK, Haese NN, Sulgey G, Medica S, Smith JL, Zhang S, Ahmad F, Karyakarte S, Rasmussen L, DeFilippis V, Tekwani B, Bostwick R, Suto MJ, Hirsch AJ, Morrison TE, Heise MT, Augelli-Szafran CE, Streblow DN, Pathak AK, Moukha-Chafiq O. Garzan A, et al. Among authors: augelli szafran ce. J Med Chem. 2024 Dec 12;67(23):20858-20878. doi: 10.1021/acs.jmedchem.4c01073. Epub 2024 Dec 2. J Med Chem. 2024. PMID: 39621435
Identification of pyrimidine structure-based compounds as allosteric ligands of the dopamine transporter as therapeutic agents for NeuroHIV.
Jimenez-Torres AC, Hastie JA, Davis SE, Porter KD, Lei B, Moukha-Chafiq O, Zhang S, Nguyen TH, Ananthan S, Augelli-Szafran CE, Zhu J. Jimenez-Torres AC, et al. Among authors: augelli szafran ce. J Pharmacol Exp Ther. 2024 Sep 16:JPET-AR-2024-002138. doi: 10.1124/jpet.124.002138. Online ahead of print. J Pharmacol Exp Ther. 2024. PMID: 39284625 Free article.
Development of small-molecule Tau-SH3 interaction inhibitors that prevent amyloid-β toxicity and network hyperexcitability.
Roth JR, Rush T, Thompson SJ, Aldaher AR, Dunn TB, Mesina JS, Cochran JN, Boyle NR, Dean HB, Yang Z, Pathak V, Ruiz P, Wu M, Day JJ, Bostwick JR, Suto MJ, Augelli-Szafran CE, Roberson ED. Roth JR, et al. Among authors: augelli szafran ce. Neurotherapeutics. 2024 Jan;21(1):e00291. doi: 10.1016/j.neurot.2023.10.001. Epub 2023 Dec 19. Neurotherapeutics. 2024. PMID: 38241154 Free PMC article.
Novel Allosteric Modulator Southern Research Institute-32743 Reverses HIV-1 Transactivator of Transcription-Induced Increase in Dopamine Release in the Caudate Putamen of Inducible Transactivator of Transcription Transgenic Mice.
Davis SE, Ferris MJ, Ananthan S, Augelli-Szafran CE, Zhu J. Davis SE, et al. Among authors: augelli szafran ce. J Pharmacol Exp Ther. 2023 Feb;384(2):306-314. doi: 10.1124/jpet.122.001291. Epub 2022 Dec 1. J Pharmacol Exp Ther. 2023. PMID: 36456195 Free PMC article.
Identification of Cytoprotective Small-Molecule Inducers of Heme-Oxygenase-1.
Ghajar-Rahimi G, Traylor AM, Mathew B, Bostwick JR, Nebane NM, Zmijewska AA, Esman SK, Thukral S, Zhai L, Sambandam V, Cowell RM, Suto MJ, George JF, Augelli-Szafran CE, Agarwal A. Ghajar-Rahimi G, et al. Among authors: augelli szafran ce. Antioxidants (Basel). 2022 Sep 23;11(10):1888. doi: 10.3390/antiox11101888. Antioxidants (Basel). 2022. PMID: 36290611 Free PMC article.
SRI-32743, a novel allosteric modulator, attenuates HIV-1 Tat protein-induced inhibition of the dopamine transporter and alleviates the potentiation of cocaine reward in HIV-1 Tat transgenic mice.
Zhu J, Quizon PM, Wang Y, Adeniran CA, Strauss MJ, Jiménez-Torres AC, Patel P, Cirino TJ, Eans SO, Hammond HR, Deliscar LS, O'Hara P, Saini SK, Ofori E, Vekariya RH, Zhang S, Moukha-Chafiq O, Nguyen TH, Ananthan S, Augelli-Szafran CE, Zhan CG, McLaughlin JP. Zhu J, et al. Among authors: augelli szafran ce. Neuropharmacology. 2022 Dec 1;220:109239. doi: 10.1016/j.neuropharm.2022.109239. Epub 2022 Sep 17. Neuropharmacology. 2022. PMID: 36126727
Novel Compound Inhibitors of HIV-1NL4-3 Vpu.
Robinson CA, Lyddon TD, Gil HM, Evans DT, Kuzmichev YV, Richard J, Finzi A, Welbourn S, Rasmussen L, Nebane NM, Gupta VV, Ananthan S, Cai Z, Wonderlich ER, Augelli-Szafran CE, Bostwick R, Ptak RG, Schader SM, Johnson MC. Robinson CA, et al. Among authors: augelli szafran ce. Viruses. 2022 Apr 15;14(4):817. doi: 10.3390/v14040817. Viruses. 2022. PMID: 35458546 Free PMC article.
53 results