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Boosting Vaccine Research: The 16-Year Journey of TRANSVAC Vaccine Infrastructure.
Martin W, Luís C, Jungbluth S, Slezak M, Verreck FAW, Spiegel H, Guzman CA, Roldão A, Carrondo MJT, Van der Ley P, Segalés J, Dockrell HM, Ho MM, Pedersen GK, Lawrenz M, Olesen OF. Martin W, et al. Among authors: lawrenz m. Vaccines (Basel). 2024 Dec 22;12(12):1446. doi: 10.3390/vaccines12121446. Vaccines (Basel). 2024. PMID: 39772106 Free article. Review.
Approaches for the Inactivation of Yersinia pestis.
Brady A, Tomaszewski M, Garrison TM, Lawrenz MB. Brady A, et al. Among authors: lawrenz mb. Appl Biosaf. 2024 Dec 16;29(4):221-231. doi: 10.1089/apb.2023.0022. eCollection 2024 Dec. Appl Biosaf. 2024. PMID: 39735406
Structure-Based Discovery and Development of Highly Potent Dihydroorotate Dehydrogenase Inhibitors for Malaria Chemoprevention.
Nie Z, Bonnert R, Tsien J, Deng X, Higgs C, El Mazouni F, Zhang X, Li R, Ho N, Feher V, Paulsen J, Shackleford DM, Katneni K, Chen G, Ng ACF, McInerney M, Wang W, Saunders J, Collins D, Yan D, Li P, Campbell M, Patil R, Ghoshal A, Mondal P, Kundu A, Chittimalla R, Mahadeva M, Kokkonda S, White J, Das R, Mukherjee P, Angulo-Barturen I, Jiménez-Díaz MB, Malmstrom R, Lawrenz M, Rodriguez-Granillo A, Rathod PK, Tomchick DR, Palmer MJ, Laleu B, Qin T, Charman SA, Phillips MA. Nie Z, et al. Among authors: lawrenz m. J Med Chem. 2025 Jan 9;68(1):590-637. doi: 10.1021/acs.jmedchem.4c02394. Epub 2024 Dec 22. J Med Chem. 2025. PMID: 39710971
In Silico Enabled Discovery of KAI-11101, a Preclinical DLK Inhibitor for the Treatment of Neurodegenerative Disease and Neuronal Injury.
Lagiakos HR, Zou Y, Igawa H, Therrien E, Lawrenz M, Kato M, Svensson M, Gray F, Jensen K, Dahlgren MK, Pelletier RD, Dingley K, Bell JA, Liu Z, Jiang Y, Zhou H, Skene RJ, Nie Z. Lagiakos HR, et al. Among authors: lawrenz m. J Med Chem. 2024 Dec 13. doi: 10.1021/acs.jmedchem.4c02074. Online ahead of print. J Med Chem. 2024. PMID: 39670820
Distinct Mechanisms of Type 3 Secretion System Recognition Control LTB4 Synthesis in Neutrophils versus Macrophages.
Brady A, Mora-Martinez LC, Hammond B, Haribabu B, Uriarte SM, Lawrenz MB. Brady A, et al. Among authors: lawrenz mb. bioRxiv [Preprint]. 2024 Jul 2:2024.07.01.601466. doi: 10.1101/2024.07.01.601466. bioRxiv. 2024. Update in: PLoS Pathog. 2024 Oct 18;20(10):e1012651. doi: 10.1371/journal.ppat.1012651 PMID: 39005373 Free PMC article. Updated. Preprint.
Potential business model for a European vaccine R&D infrastructure and its estimated socio-economic impact.
Jungbluth S, Martin W, Slezak M, Depraetere H, Guzman CA, Ussi A, Morrow D, Van Heuverswyn F, Arnouts S, Carrondo MJT, Olesen O, Ottenhoff THM, Dockrell HM, Ho MM, Dobly A, Christensen D, Segalés J, Laurent F, Lantier F, Stockhofe-Zurwieden N, Morelli F, Langermans JAM, Verreck FAW, Le Grand R, Sloots A, Medaglini D, Lawrenz M, Collin N. Jungbluth S, et al. Among authors: lawrenz m. F1000Res. 2023 Oct 24;12:1401. doi: 10.12688/f1000research.141399.1. eCollection 2023. F1000Res. 2023. PMID: 38298529 Free PMC article.
84 results