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Canine Best disease as a translational model.
Aguirre GD, Beltran WA. Aguirre GD, et al. Eye (Lond). 2025 Jan 7. doi: 10.1038/s41433-024-03578-0. Online ahead of print. Eye (Lond). 2025. PMID: 39774293 Review.
CREB1/ATF1 activation in photoreceptor degeneration and protection.
Beltran WA, Allore HG, Johnson E, Towle V, Tao W, Acland GM, Aguirre GD, Zeiss CJ. Beltran WA, et al. Among authors: aguirre gd. Invest Ophthalmol Vis Sci. 2009 Nov;50(11):5355-63. doi: 10.1167/iovs.09-3741. Epub 2009 Jul 30. Invest Ophthalmol Vis Sci. 2009. PMID: 19643965 Free PMC article.
Gene therapy rescues photoreceptor blindness in dogs and paves the way for treating human X-linked retinitis pigmentosa.
Beltran WA, Cideciyan AV, Lewin AS, Iwabe S, Khanna H, Sumaroka A, Chiodo VA, Fajardo DS, Román AJ, Deng WT, Swider M, Alemán TS, Boye SL, Genini S, Swaroop A, Hauswirth WW, Jacobson SG, Aguirre GD. Beltran WA, et al. Among authors: aguirre gd. Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):2132-7. doi: 10.1073/pnas.1118847109. Epub 2012 Jan 23. Proc Natl Acad Sci U S A. 2012. PMID: 22308428 Free PMC article.
Human retinal gene therapy for Leber congenital amaurosis shows advancing retinal degeneration despite enduring visual improvement.
Cideciyan AV, Jacobson SG, Beltran WA, Sumaroka A, Swider M, Iwabe S, Roman AJ, Olivares MB, Schwartz SB, Komáromy AM, Hauswirth WW, Aguirre GD. Cideciyan AV, et al. Among authors: aguirre gd. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E517-25. doi: 10.1073/pnas.1218933110. Epub 2013 Jan 22. Proc Natl Acad Sci U S A. 2013. PMID: 23341635 Free PMC article.
289 results