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The spatial organization of cDC1 with CD8+ T cells is critical for the response to immune checkpoint inhibitors in melanoma patients.
Gobbini E, Hubert M, Doffin AC, Eberhardt A, Hermet L, Li D, Duplouye P, Ghamry-Barrin S, Berthet J, Benboubker V, Grimont M, Sakref C, Perrot J, Tondeur G, Harou O, Lopez J, Dubois B, Dalle S, Caux C, Caramel J, Valladeau-Guilemond J. Gobbini E, et al. Among authors: hubert m. Cancer Immunol Res. 2025 Jan 7. doi: 10.1158/2326-6066.CIR-24-0421. Online ahead of print. Cancer Immunol Res. 2025. PMID: 39774795
IFN-III is selectively produced by cDC1 and predicts good clinical outcome in breast cancer.
Hubert M, Gobbini E, Couillault C, Manh TV, Doffin AC, Berthet J, Rodriguez C, Ollion V, Kielbassa J, Sajous C, Treilleux I, Tredan O, Dubois B, Dalod M, Bendriss-Vermare N, Caux C, Valladeau-Guilemond J. Hubert M, et al. Sci Immunol. 2020 Apr 17;5(46):eaav3942. doi: 10.1126/sciimmunol.aav3942. Epub 2020 Apr 17. Sci Immunol. 2020. PMID: 32303573
Guidelines for visualization and analysis of DC in tissues using multiparameter fluorescence microscopy imaging methods.
Bayerl F, Bejarano DA, Bertacchi G, Doffin AC, Gobbini E, Hubert M, Li L, Meiser P, Pedde AM, Posch W, Rupp L, Schlitzer A, Schmitz M, Schraml BU, Uderhardt S, Valladeau-Guilemond J, Wilflingseder D, Zaderer V, Böttcher JP. Bayerl F, et al. Among authors: hubert m. Eur J Immunol. 2023 Nov;53(11):e2249923. doi: 10.1002/eji.202249923. Epub 2023 Jan 9. Eur J Immunol. 2023. PMID: 36623939 Free article.
MDR1-EXPRESSING CD4+ T CELLS WITH TH1.17 FEATURES RESIST TO NEOADJUVANT CHEMOTHERAPY AND ARE ASSOCIATED WITH BREAST CANCER CLINICAL RESPONSE.
Di Roio A, Hubert M, Besson L, Bossennec M, Rodriguez C, Grinberg-Bleyer Y, Lalle G, Moudombi L, Schneider R, Degletagne C, Treilleux I, Campbell DJ, Metzger S, Duhen T, Trédan O, Caux C, Ménétrier-Caux C. Di Roio A, et al. Among authors: hubert m. J Immunother Cancer. 2023 Nov;11(11):e007733. doi: 10.1136/jitc-2023-007733. J Immunother Cancer. 2023. PMID: 37940345 Free PMC article.
CD163+ tumor-associated macrophage accumulation in breast cancer patients reflects both local differentiation signals and systemic skewing of monocytes.
Ramos RN, Rodriguez C, Hubert M, Ardin M, Treilleux I, Ries CH, Lavergne E, Chabaud S, Colombe A, Trédan O, Guedes HG, Laginha F, Richer W, Piaggio E, Barbuto JAM, Caux C, Ménétrier-Caux C, Bendriss-Vermare N. Ramos RN, et al. Among authors: hubert m. Clin Transl Immunology. 2020 Feb 13;9(2):e1108. doi: 10.1002/cti2.1108. eCollection 2020. Clin Transl Immunology. 2020. PMID: 32082570 Free PMC article.
384 results