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Page 1
Enhanced RNAi does not provide efficient innate antiviral immunity in mice.
Kulmann MIR, Taborska E, Benköova B, Palus M, Drobek A, Horvat F, Pasulka J, Malik R, Salyova E, Hönig V, Pellerova M, Borsanyiova M, Nedvedova L, Stepanek O, Bopegamage S, Ruzek D, Svoboda P. Kulmann MIR, et al. Among authors: drobek a. Nucleic Acids Res. 2025 Jan 7;53(1):gkae1288. doi: 10.1093/nar/gkae1288. Nucleic Acids Res. 2025. PMID: 39778869 Free PMC article.
CCDC134 controls TLR biogenesis through the ER chaperone Gp96.
Bernaleau L, Drobek M, Blank F, Walch P, Delacrétaz M, Drobek A, Monguió-Tortajada M, Broz P, Majer O, Rebsamen M. Bernaleau L, et al. Among authors: drobek a. J Exp Med. 2025 Mar 3;222(3):e20240825. doi: 10.1084/jem.20240825. Epub 2024 Dec 10. J Exp Med. 2025. PMID: 39656203 Free PMC article.
TBK1-associated adapters TANK and AZI2 protect mice against TNF-induced cell death and severe autoinflammatory diseases.
Ujevic A, Knizkova D, Synackova A, Pribikova M, Trivic T, Dalinskaya A, Drobek A, Niederlova V, Paprckova D, De Guia R, Kasparek P, Prochazka J, Labaj J, Fedosieieva O, Roeck BF, Mihola O, Trachtulec Z, Sedlacek R, Stepanek O, Draber P. Ujevic A, et al. Among authors: drobek a. Nat Commun. 2024 Nov 19;15(1):10013. doi: 10.1038/s41467-024-54399-4. Nat Commun. 2024. PMID: 39562788 Free PMC article.
ABIN1 is a negative regulator of effector functions in cytotoxic T cells.
Janusova S, Paprckova D, Michalik J, Uleri V, Drobek A, Salyova E, Chorfi L, Neuwirth A, Andreyeva A, Prochazka J, Sedlacek R, Draber P, Stepanek O. Janusova S, et al. Among authors: drobek a. EMBO Rep. 2024 Aug;25(8):3456-3485. doi: 10.1038/s44319-024-00179-6. Epub 2024 Jun 14. EMBO Rep. 2024. PMID: 38877170 Free PMC article.
Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells.
Horkova V, Drobek A, Paprckova D, Niederlova V, Prasai A, Uleri V, Glatzova D, Kraller M, Cesnekova M, Janusova S, Salyova E, Tsyklauri O, Kadlecek TA, Krizova K, Platzer R, Schober K, Busch DH, Weiss A, Huppa JB, Stepanek O. Horkova V, et al. Among authors: drobek a. Nat Immunol. 2023 Jan;24(1):174-185. doi: 10.1038/s41590-022-01366-0. Epub 2022 Dec 23. Nat Immunol. 2023. PMID: 36564464 Free PMC article.
Self-reactivity of CD8 T-cell clones determines their differentiation status rather than their responsiveness in infections.
Paprckova D, Niederlova V, Moudra A, Drobek A, Pribikova M, Janusova S, Schober K, Neuwirth A, Michalik J, Huranova M, Horkova V, Cesnekova M, Simova M, Prochazka J, Balounova J, Busch DH, Sedlacek R, Schwarzer M, Stepanek O. Paprckova D, et al. Among authors: drobek a. Front Immunol. 2022 Oct 6;13:1009198. doi: 10.3389/fimmu.2022.1009198. eCollection 2022. Front Immunol. 2022. PMID: 36275704 Free PMC article.
CMTM4 is a subunit of the IL-17 receptor and mediates autoimmune pathology.
Knizkova D, Pribikova M, Draberova H, Semberova T, Trivic T, Synackova A, Ujevic A, Stefanovic J, Drobek A, Huranova M, Niederlova V, Tsyklauri O, Neuwirth A, Tureckova J, Stepanek O, Draber P. Knizkova D, et al. Among authors: drobek a. Nat Immunol. 2022 Nov;23(11):1644-1652. doi: 10.1038/s41590-022-01325-9. Epub 2022 Oct 21. Nat Immunol. 2022. PMID: 36271145 Free PMC article.
22 results