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Dual-targeting CRISPR-CasRx reduces C9orf72 ALS/FTD sense and antisense repeat RNAs in vitro and in vivo.
Kempthorne L, Vaizoglu D, Cammack AJ, Carcolé M, Roberts MJ, Mikheenko A, Fisher A, Suklai P, Muralidharan B, Kroll F, Moens TG, Yshii L, Verschoren S, Hölbling BV, Moreira FC, Katona E, Coneys R, de Oliveira P, Zhang YJ, Jansen K, Daughrity LM, McGown A, Ramesh TM, Van Den Bosch L, Lignani G, Rahim AA, Coyne AN, Petrucelli L, Rihel J, Isaacs AM. Kempthorne L, et al. Among authors: rahim aa. Nat Commun. 2025 Jan 8;16(1):459. doi: 10.1038/s41467-024-55550-x. Nat Commun. 2025. PMID: 39779704 Free PMC article.
An autonucleolytic suspension HEK293F host cell line for high-titer serum-free AAV5 and AAV9 production with reduced levels of DNA impurity.
Howe G, Bal M, Wasmuth M, Massaro G, Rahim AA, Ali S, Rivera M, Schofield DM, Omotosho A, Ward J, Keshavarz-Moore E, Mason C, Nesbeth DN. Howe G, et al. Among authors: rahim aa. Mol Ther Methods Clin Dev. 2024 Aug 12;32(3):101317. doi: 10.1016/j.omtm.2024.101317. eCollection 2024 Sep 12. Mol Ther Methods Clin Dev. 2024. PMID: 39257529 Free PMC article.
Predictors of musculoskeletal disorders among special education teachers in Sabah, Malaysia.
Jeffree MS, Abdul Rahim AA, Daud DMA, Pang N, Sazali MF, Sudi S, Liau SN, Wong EEL, Peter HF, Amat SZA, Chok S, Abdelhafez MMA, Lukman KA, Saad I, Hassan MR, Noordin R. Jeffree MS, et al. Among authors: abdul rahim aa. Heliyon. 2024 May 14;10(10):e30873. doi: 10.1016/j.heliyon.2024.e30873. eCollection 2024 May 30. Heliyon. 2024. PMID: 38826737 Free PMC article.
155 results