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Page 1
Reduced PI3K(p110α) induces atrial myopathy, and PI3K-related lipids are dysregulated in athletes with atrial fibrillation.
Bass-Stringer S, Bernardo BC, Yildiz GS, Matsumoto A, Kiriazis H, Harmawan CA, Tai CMK, Chooi R, Bottrell L, Ezeani M, Donner DG, D'Elia AA, Ooi JYY, Mellett NA, Luo J, Masterman EI, Janssens K, Olshansky G, Howden EJ, Cross JH, Hagemeyer CE, Lin RCY, Thomas CJ, Magor GW, Perkins AC, Marwick TH, Kawakami H, Meikle PJ, Greening DW, Weeks KL, La Gerche A, Tham YK, McMullen JR. Bass-Stringer S, et al. Among authors: mellett na. J Sport Health Sci. 2025 Jan 16:101023. doi: 10.1016/j.jshs.2025.101023. Online ahead of print. J Sport Health Sci. 2025. PMID: 39826614 Free article.
An optimized plasmalogen modulating dietary supplement provides greater protection in a male than female mouse model of dilated cardiomyopathy.
Belkin TG, Masterman EI, Yildiz GS, Kiriazis H, Mellett NA, Cross J, Grigolon K, Dogra A, Donner D, Chooi R, Liang A, Kompa AR, Sadoshima J, Edgley AJ, Greening DW, Meikle PJ, Tham YK, McMullen JR. Belkin TG, et al. Among authors: mellett na. J Mol Cell Cardiol Plus. 2024 Dec 4;11:100273. doi: 10.1016/j.jmccpl.2024.100273. eCollection 2025 Mar. J Mol Cell Cardiol Plus. 2024. PMID: 39802264 Free PMC article.
Consuming a modified Mediterranean ketogenic diet reverses the peripheral lipid signature of Alzheimer's disease in humans.
Neth BJ, Huynh K, Giles C, Wang T, Mellett NA, Duong T, Blach C, Schimmel L, Register TC, Blennow K, Zetterberg H, Batra R, Schweickart A, Dilmore AH, Martino C, Arnold M, Krumsiek J, Han X, Dorrestein PC, Knight R, Meikle PJ, Craft S, Kaddurah-Daouk R. Neth BJ, et al. Among authors: mellett na. Commun Med (Lond). 2025 Jan 9;5(1):11. doi: 10.1038/s43856-024-00682-w. Commun Med (Lond). 2025. PMID: 39779882 Free PMC article.
Time restricted feeding alters the behavioural and physiological outcomes to repeated mild traumatic brain injury in male and female rats.
Zaini A, Morgan PK, Cardwell B, Vlassopoulos E, Sgro M, Li CN, Salberg S, Mellett NA, Christensen J, Meikle PJ, Murphy AJ, Marsland BJ, Mychasiuk R, Yamakawa GR. Zaini A, et al. Among authors: mellett na. Exp Neurol. 2024 Dec 9;385:115108. doi: 10.1016/j.expneurol.2024.115108. Online ahead of print. Exp Neurol. 2024. PMID: 39662793 Free article. No abstract available.
Efficient megakaryopoiesis and platelet production require phospholipid remodeling and PUFA uptake through CD36.
Barrachina MN, Pernes G, Becker IC, Allaeys I, Hirsch TI, Groeneveld DJ, Khan AO, Freire D, Guo K, Carminita E, Morgan PK, Collins TJC, Mellett NA, Wei Z, Almazni I, Italiano JE, Luyendyk J, Meikle PJ, Puder M, Morgan NV, Boilard E, Murphy AJ, Machlus KR. Barrachina MN, et al. Among authors: mellett na. Nat Cardiovasc Res. 2023 Aug;2(8):746-763. doi: 10.1038/s44161-023-00305-y. Epub 2023 Jul 17. Nat Cardiovasc Res. 2023. PMID: 39195958
A lipidomic based metabolic age score captures cardiometabolic risk independent of chronological age.
Wang T, Beyene HB, Yi C, Cinel M, Mellett NA, Olshansky G, Meikle TG, Wu J, Dakic A, Watts GF, Hung J, Hui J, Beilby J, Blangero J, Kaddurah-Daouk R, Salim A, Moses EK, Shaw JE, Magliano DJ, Huynh K, Giles C, Meikle PJ. Wang T, et al. Among authors: mellett na. EBioMedicine. 2024 Jul;105:105199. doi: 10.1016/j.ebiom.2024.105199. Epub 2024 Jun 20. EBioMedicine. 2024. PMID: 38905750 Free PMC article.
Development and validation of a plasmalogen score as an independent modifiable marker of metabolic health: population based observational studies and a placebo-controlled cross-over study.
Beyene HB, Huynh K, Wang T, Paul S, Cinel M, Mellett NA, Olshansky G, Meikle TG, Watts GF, Hung J, Hui J, Beilby J, Blangero J, Moses EK, Shaw JE, Magliano DJ, Giles C, Meikle PJ. Beyene HB, et al. Among authors: mellett na. EBioMedicine. 2024 Jul;105:105187. doi: 10.1016/j.ebiom.2024.105187. Epub 2024 Jun 10. EBioMedicine. 2024. PMID: 38861870 Free PMC article.
A lipid atlas of human and mouse immune cells provides insights into ferroptosis susceptibility.
Morgan PK, Pernes G, Huynh K, Giles C, Paul S, Smith AAT, Mellett NA, Liang A, van Buuren-Milne T, Veiga CB, Collins TJC, Xu Y, Lee MKS, De Silva TM, Meikle PJ, Lancaster GI, Murphy AJ. Morgan PK, et al. Among authors: mellett na. Nat Cell Biol. 2024 Apr;26(4):645-659. doi: 10.1038/s41556-024-01377-z. Epub 2024 Apr 8. Nat Cell Biol. 2024. PMID: 38589531
ACAD10 is not required for metformin's metabolic actions or for maintenance of whole-body metabolism in C57BL/6J mice.
Yew MJ, Heywood SE, Ng J, West OM, Pal M, Kueh A, Lancaster GI, Myers S, Yang C, Liu Y, Reibe S, Mellett NA, Meikle PJ, Febbraio MA, Greening DW, Drew BG, Henstridge DC. Yew MJ, et al. Among authors: mellett na. Diabetes Obes Metab. 2024 May;26(5):1731-1745. doi: 10.1111/dom.15484. Epub 2024 Feb 13. Diabetes Obes Metab. 2024. PMID: 38351663
70 results