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Comparison of Plasma p-tau217 and [18F]FDG-PET for Identifying Alzheimer Disease in People With Early-Onset or Atypical Dementia.
Quispialaya KM, Therriault J, Aliaga A, Benedet AL, Ashton NJ, Karikari T, Cassa Macedo A, Rahmouni N, Tissot C, Fernandez Arias J, Wang YT, Trudel L, Hosseini SA, Matsudaira T, Chan T, Pascoal T, Gilfix B, Vitali P, Zimmer ER, Provost K, Soucy JP, Gauthier S, Zetterberg H, Jean-Claude BJ, Blennow K, Rosa-Neto P. Quispialaya KM, et al. Among authors: soucy jp. Neurology. 2025 Jan 28;104(2):e210211. doi: 10.1212/WNL.0000000000210211. Epub 2024 Dec 23. Neurology. 2025. PMID: 39715476 Free PMC article.
Comparison Between Brain and Cerebellar Autoradiography Using [18F]Flortaucipir, [18F]MK6240, and [18F]PI2620 in Postmortem Human Brain Tissue.
Aliaga A, Therriault J, Quispialaya KM, Aliaga A, Hopewell R, Rahmouni N, Macedo AC, Kunach P, Soucy JP, Massarweh G, Diaz AA, Pascoal TA, Rocha A, Guiot MC, Machado LS, De Bastiani MA, de Souza DG, Souza DO, Gauthier S, Zimmer ER, Rosa-Neto P. Aliaga A, et al. Among authors: soucy jp. J Nucl Med. 2025 Jan 3;66(1):123-129. doi: 10.2967/jnumed.124.267539. J Nucl Med. 2025. PMID: 39477493
Plasma phosphorylated tau181 outperforms [18F] fluorodeoxyglucose positron emission tomography in the identification of early Alzheimer disease.
Quispialaya KM, Therriault J, Aliaga A, Tissot C, Servaes S, Rahmouni N, Karikari TK, Benedet AL, Ashton NJ, Macedo AC, Lussier FZ, Stevenson J, Wang YT, Arias JF, Hosseini A, Matsudaira T, Jean-Claude B, Gilfix BM, Zimmer ER, Soucy JP, Pascoal TA, Gauthier S, Zetterberg H, Blennow K, Rosa-Neto P; Alzheimer's Disease Neuroimaging Initiative. Quispialaya KM, et al. Among authors: soucy jp. Eur J Neurol. 2024 Dec;31(12):e16255. doi: 10.1111/ene.16255. Epub 2024 Oct 24. Eur J Neurol. 2024. PMID: 39447157 Free PMC article.
Cryo-EM structure of Alzheimer's disease tau filaments with PET ligand MK-6240.
Kunach P, Vaquer-Alicea J, Smith MS, Monistrol J, Hopewell R, Moquin L, Therriault J, Tissot C, Rahmouni N, Massarweh G, Soucy JP, Guiot MC, Shoichet BK, Rosa-Neto P, Diamond MI, Shahmoradian SH. Kunach P, et al. Among authors: soucy jp. Nat Commun. 2024 Oct 1;15(1):8497. doi: 10.1038/s41467-024-52265-x. Nat Commun. 2024. PMID: 39353896 Free PMC article.
The neurophysiological brain-fingerprint of Parkinson's disease.
da Silva Castanheira J, Wiesman AI, Hansen JY, Misic B, Baillet S; PREVENT-AD Research Group; Quebec Parkinson Network. da Silva Castanheira J, et al. EBioMedicine. 2024 Jul;105:105201. doi: 10.1016/j.ebiom.2024.105201. Epub 2024 Jun 21. EBioMedicine. 2024. PMID: 38908100 Free PMC article.
Tau follows principal axes of functional and structural brain organization in Alzheimer's disease.
Ottoy J, Kang MS, Tan JXM, Boone L, Vos de Wael R, Park BY, Bezgin G, Lussier FZ, Pascoal TA, Rahmouni N, Stevenson J, Fernandez Arias J, Therriault J, Hong SJ, Stefanovic B, McLaurin J, Soucy JP, Gauthier S, Bernhardt BC, Black SE, Rosa-Neto P, Goubran M. Ottoy J, et al. Among authors: soucy jp. Nat Commun. 2024 Jun 12;15(1):5031. doi: 10.1038/s41467-024-49300-2. Nat Commun. 2024. PMID: 38866759 Free PMC article.
Plasma p-tau217 predicts cognitive impairments up to ten years before onset in normal older adults.
Yakoub Y, Gonzalez-Ortiz F, Ashton NJ, Déry C, Strikwerda-Brown C, St-Onge F, Ourry V, Schöll M, Geddes MR, Ducharme S, Montembeault M, Rosa-Neto P, Soucy JP, Breitner JCS, Zetterberg H, Blennow K, Poirier J, Villeneuve S; PREVENT-AD Research Group. Yakoub Y, et al. Among authors: soucy jp. medRxiv [Preprint]. 2024 May 9:2024.05.09.24307120. doi: 10.1101/2024.05.09.24307120. medRxiv. 2024. PMID: 38766113 Free PMC article. Preprint.
218 results