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Single-Cell Heterogeneity of EGFR Pathway Is Linked to Unique Signatures of Drug Response and Malignancy in Patient Derived Glioblastoma Stem Cells.
Masterman-Smith MD, Graham NA, Panosyan EH, Mottahedeh J, Samuels ER, Nunez A, Phillips T, Choe M, Cloughesy TF, Lazareff JA, Liau LM, Yong WH, Graeber TG, Kornblum HI, Lang MF, Li Y, Sun J. Masterman-Smith MD, et al. Among authors: cloughesy tf. Cancer Res Treat. 2025 Jan 7. doi: 10.4143/crt.2024.859. Online ahead of print. Cancer Res Treat. 2025. PMID: 39788641 Free article.
Autocrine endothelin-3/endothelin receptor B signaling maintains cellular and molecular properties of glioblastoma stem cells.
Liu Y, Ye F, Yamada K, Tso JL, Zhang Y, Nguyen DH, Dong Q, Soto H, Choe J, Dembo A, Wheeler H, Eskin A, Schmid I, Yong WH, Mischel PS, Cloughesy TF, Kornblum HI, Nelson SF, Liau LM, Tso CL. Liu Y, et al. Among authors: cloughesy tf. Mol Cancer Res. 2011 Dec;9(12):1668-85. doi: 10.1158/1541-7786.MCR-10-0563. Epub 2011 Oct 19. Mol Cancer Res. 2011. PMID: 22013079 Free PMC article.
D-2-HG Inhibits IDH1mut Glioma Growth via FTO Inhibition and Resultant m6A Hypermethylation.
Pianka ST, Li T, Prins TJ, Eldred BSC, Kevan BM, Liang H, Zapanta Rinonos S, Kornblum HI, Nathanson DA, Pellegrini M, Liau LM, Nghiemphu PL, Cloughesy TF, Lai A. Pianka ST, et al. Among authors: cloughesy tf. Cancer Res Commun. 2024 Mar 22;4(3):876-894. doi: 10.1158/2767-9764.CRC-23-0271. Cancer Res Commun. 2024. PMID: 38445960 Free PMC article.
Primary glioblastomas express mesenchymal stem-like properties.
Tso CL, Shintaku P, Chen J, Liu Q, Liu J, Chen Z, Yoshimoto K, Mischel PS, Cloughesy TF, Liau LM, Nelson SF. Tso CL, et al. Among authors: cloughesy tf. Mol Cancer Res. 2006 Sep;4(9):607-19. doi: 10.1158/1541-7786.MCR-06-0005. Mol Cancer Res. 2006. PMID: 16966431 Free article.
Maternal embryonic leucine zipper kinase is a key regulator of the proliferation of malignant brain tumors, including brain tumor stem cells.
Nakano I, Masterman-Smith M, Saigusa K, Paucar AA, Horvath S, Shoemaker L, Watanabe M, Negro A, Bajpai R, Howes A, Lelievre V, Waschek JA, Lazareff JA, Freije WA, Liau LM, Gilbertson RJ, Cloughesy TF, Geschwind DH, Nelson SF, Mischel PS, Terskikh AV, Kornblum HI. Nakano I, et al. Among authors: cloughesy tf. J Neurosci Res. 2008 Jan;86(1):48-60. doi: 10.1002/jnr.21471. J Neurosci Res. 2008. PMID: 17722061
366 results