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s-HBEGF/SIRT1 circuit-dictated crosstalk between vascular endothelial cells and keratinocytes mediates sorafenib-induced hand-foot skin reaction that can be reversed by nicotinamide.
Luo P, Yan H, Chen X, Zhang Y, Zhao Z, Cao J, Zhu Y, Du J, Xu Z, Zhang X, Zeng S, Yang B, Ma S, He Q. Luo P, et al. Among authors: zhang x, zhang y. Cell Res. 2020 Sep;30(9):779-793. doi: 10.1038/s41422-020-0309-6. Epub 2020 Apr 15. Cell Res. 2020. PMID: 32296111 Free PMC article.
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