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Radiosynthesis and evaluation of novel 18F labeled PET ligands for imaging monoacylglycerol lipase.
Li Y, Mori W, Chaudhary A, Zhao C, Yamasaki T, Zhang Z, Feng S, Ware T, Rong J, Fujinaga M, Chen J, Kumata K, Zhang Y, Hu K, Xie L, Zhou X, Song Z, Gao Y, Sun Z, Patel JS, Zhai C, Yuan KY, Collier TL, Ran C, Collin L, Haider A, Grether U, Wittwer MB, Cravatt BF, Zhang MR, Liang SH. Li Y, et al. Among authors: cravatt bf. Eur J Med Chem. 2025 Jan 4;285:117246. doi: 10.1016/j.ejmech.2025.117246. Online ahead of print. Eur J Med Chem. 2025. PMID: 39793441
Excessive alcohol intake produces persistent mechanical allodynia and dysregulates the endocannabinoid system in the lumbar dorsal root ganglia of genetically-selected Marchigian Sardinian alcohol-preferring rats.
Borgonetti V, Vozella V, Ware T, Cruz B, Bullard R, Cravatt BF, Galeotti N, Roberto M. Borgonetti V, et al. Among authors: cravatt bf. Pharmacol Res. 2024 Nov;209:107462. doi: 10.1016/j.phrs.2024.107462. Epub 2024 Oct 11. Pharmacol Res. 2024. PMID: 39396766 Free article.
Chemical probes for the identification of the molecular targets of honokiol.
Vázquez-Villa H, Rueda-Zubiaurre A, Fernández D, Foronda R, Parker CG, Cravatt BF, Martín-Fontecha M, Ortega-Gutiérrez S. Vázquez-Villa H, et al. Among authors: cravatt bf. Eur J Med Chem. 2025 Feb 5;283:117102. doi: 10.1016/j.ejmech.2024.117102. Epub 2024 Nov 24. Eur J Med Chem. 2025. PMID: 39616692 Free article.
Sexually dimorphic effects of monoacylglycerol lipase inhibitor MJN110 on stress-related behaviour and drinking in Marchigian Sardinian alcohol-preferring rats.
Vozella V, Cruz B, Feldman HC, Bullard R, Bianchi PC, Natividad LA, Cravatt BF, Zorrilla EP, Ciccocioppo R, Roberto M. Vozella V, et al. Among authors: cravatt bf. Br J Pharmacol. 2023 Dec;180(24):3130-3145. doi: 10.1111/bph.16197. Epub 2023 Aug 19. Br J Pharmacol. 2023. PMID: 37488777 Free PMC article.
Collateral lethality between HDAC1 and HDAC2 exploits cancer-specific NuRD complex vulnerabilities.
Zhang Y, Remillard D, Onubogu U, Karakyriakou B, Asiaban JN, Ramos AR, Bowland K, Bishop TR, Barta PA, Nance S, Durbin AD, Ott CJ, Janiszewska M, Cravatt BF, Erb MA. Zhang Y, et al. Among authors: cravatt bf. Nat Struct Mol Biol. 2023 Aug;30(8):1160-1171. doi: 10.1038/s41594-023-01041-4. Epub 2023 Jul 24. Nat Struct Mol Biol. 2023. PMID: 37488358 Free PMC article.
592 results