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Page 1
Radiosynthesis and evaluation of novel 18F labeled PET ligands for imaging monoacylglycerol lipase.
Li Y, Mori W, Chaudhary A, Zhao C, Yamasaki T, Zhang Z, Feng S, Ware T, Rong J, Fujinaga M, Chen J, Kumata K, Zhang Y, Hu K, Xie L, Zhou X, Song Z, Gao Y, Sun Z, Patel JS, Zhai C, Yuan KY, Collier TL, Ran C, Collin L, Haider A, Grether U, Wittwer MB, Cravatt BF, Zhang MR, Liang SH. Li Y, et al. Among authors: grether u. Eur J Med Chem. 2025 Jan 4;285:117246. doi: 10.1016/j.ejmech.2025.117246. Online ahead of print. Eur J Med Chem. 2025. PMID: 39793441
Selective Photoaffinity Probe That Enables Assessment of Cannabinoid CB2 Receptor Expression and Ligand Engagement in Human Cells.
Soethoudt M, Stolze SC, Westphal MV, van Stralen L, Martella A, van Rooden EJ, Guba W, Varga ZV, Deng H, van Kasteren SI, Grether U, IJzerman AP, Pacher P, Carreira EM, Overkleeft HS, Ioan-Facsinay A, Heitman LH, van der Stelt M. Soethoudt M, et al. Among authors: grether u. J Am Chem Soc. 2018 May 16;140(19):6067-6075. doi: 10.1021/jacs.7b11281. Epub 2018 Feb 16. J Am Chem Soc. 2018. PMID: 29420021 Free PMC article.
Structure-Activity Relationship Studies of Pyridine-Based Ligands and Identification of a Fluorinated Derivative for Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors.
Haider A, Kretz J, Gobbi L, Ahmed H, Atz K, Bürkler M, Bartelmus C, Fingerle J, Guba W, Ullmer C, Honer M, Knuesel I, Weber M, Brink A, Herde AM, Keller C, Schibli R, Mu L, Grether U, Ametamey SM. Haider A, et al. Among authors: grether u. J Med Chem. 2019 Dec 26;62(24):11165-11181. doi: 10.1021/acs.jmedchem.9b01280. Epub 2019 Dec 5. J Med Chem. 2019. PMID: 31751140
Identification and Preclinical Development of a 2,5,6-Trisubstituted Fluorinated Pyridine Derivative as a Radioligand for the Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors.
Haider A, Gobbi L, Kretz J, Ullmer C, Brink A, Honer M, Woltering TJ, Muri D, Iding H, Bürkler M, Binder M, Bartelmus C, Knuesel I, Pacher P, Herde AM, Spinelli F, Ahmed H, Atz K, Keller C, Weber M, Schibli R, Mu L, Grether U, Ametamey SM. Haider A, et al. Among authors: grether u. J Med Chem. 2020 Sep 24;63(18):10287-10306. doi: 10.1021/acs.jmedchem.0c00778. Epub 2020 Sep 1. J Med Chem. 2020. PMID: 32787079
Discovery, synthesis and evaluation of novel reversible monoacylglycerol lipase radioligands bearing a morpholine-3-one scaffold.
He Y, Gobbi LC, Herde AM, Rombach D, Ritter M, Kuhn B, Wittwer MB, Heer D, Hornsperger B, Bell C, O'Hara F, Benz J, Honer M, Keller C, Collin L, Richter H, Schibli R, Grether U, Mu L. He Y, et al. Among authors: grether u. Nucl Med Biol. 2022 May-Jun;108-109:24-32. doi: 10.1016/j.nucmedbio.2022.02.002. Epub 2022 Feb 23. Nucl Med Biol. 2022. PMID: 35248850 Free article.
77 results