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266 results

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Page 1
Discovery of new inhibitors of nuclease MRE11.
Nikulenkov F, Carbain B, Biswas R, Havel S, Prochazkova J, Sisakova A, Zacpalova M, Chavdarova M, Marini V, Vsiansky V, Weisova V, Slavikova K, Biradar D, Khirsariya P, Vitek M, Sedlak D, Bartunek P, Daniel L, Brezovsky J, Damborsky J, Paruch K, Krejci L. Nikulenkov F, et al. Among authors: damborsky j. Eur J Med Chem. 2025 Jan 1;285:117226. doi: 10.1016/j.ejmech.2024.117226. Online ahead of print. Eur J Med Chem. 2025. PMID: 39793442
A computational workflow for analysis of missense mutations in precision oncology.
Khan RT, Pokorna P, Stourac J, Borko S, Arefiev I, Planas-Iglesias J, Dobias A, Pinto G, Szotkowska V, Sterba J, Slaby O, Damborsky J, Mazurenko S, Bednar D. Khan RT, et al. Among authors: damborsky j. J Cheminform. 2024 Jul 29;16(1):86. doi: 10.1186/s13321-024-00876-3. J Cheminform. 2024. PMID: 39075588 Free PMC article.
PredictONCO: a web tool supporting decision-making in precision oncology by extending the bioinformatics predictions with advanced computing and machine learning.
Stourac J, Borko S, Khan RT, Pokorna P, Dobias A, Planas-Iglesias J, Mazurenko S, Pinto G, Szotkowska V, Sterba J, Slaby O, Damborsky J, Bednar D. Stourac J, et al. Among authors: damborsky j. Brief Bioinform. 2023 Nov 22;25(1):bbad441. doi: 10.1093/bib/bbad441. Brief Bioinform. 2023. PMID: 38066711 Free PMC article.
Pathogenesis of Alzheimer's disease: Involvement of the choroid plexus.
Čarna M, Onyango IG, Katina S, Holub D, Novotny JS, Nezvedova M, Jha D, Nedelska Z, Lacovich V, Vyvere TV, Houbrechts R, Garcia-Mansfield K, Sharma R, David-Dirgo V, Vyhnalek M, Texlova K, Chaves H, Bakkar N, Pertierra L, Vinkler M, Markova H, Laczo J, Sheardova K, Hortova-Kohoutkova M, Frič J, Forte G, Kaňovsky P, Belaškova S, Damborsky J, Hort J, Seyfried NT, Bowser R, Sevlever G, Rissman RA, Smith RA, Hajduch M, Pirrotte P, Spacil Z, Dammer EB, Limbäck-Stokin C, Stokin GB. Čarna M, et al. Among authors: damborsky j. Alzheimers Dement. 2023 Aug;19(8):3537-3554. doi: 10.1002/alz.12970. Epub 2023 Feb 24. Alzheimers Dement. 2023. PMID: 36825691 Free PMC article.
Analysis of mutations in precision oncology using the automated, accurate, and user-friendly web tool PredictONCO.
Khan RT, Pokorna P, Stourac J, Borko S, Dobias A, Planas-Iglesias J, Mazurenko S, Arefiev I, Pinto G, Szotkowska V, Sterba J, Damborsky J, Slaby O, Bednar D. Khan RT, et al. Among authors: damborsky j. Comput Struct Biotechnol J. 2024 Nov 14;24:734-738. doi: 10.1016/j.csbj.2024.11.026. eCollection 2024 Dec. Comput Struct Biotechnol J. 2024. PMID: 39687752 Free PMC article.
Structural analysis of the stable form of fibroblast growth factor 2 - FGF2-STAB.
de La Bourdonnaye G, Marek M, Ghazalova T, Damborsky J, Pachl P, Brynda J, Stepankova V, Chaloupkova R. de La Bourdonnaye G, et al. Among authors: damborsky j. J Struct Biol X. 2024 Oct 24;10:100112. doi: 10.1016/j.yjsbx.2024.100112. eCollection 2024 Dec. J Struct Biol X. 2024. PMID: 39512606 Free PMC article.
266 results