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Page 1
Discovery of new inhibitors of nuclease MRE11.
Nikulenkov F, Carbain B, Biswas R, Havel S, Prochazkova J, Sisakova A, Zacpalova M, Chavdarova M, Marini V, Vsiansky V, Weisova V, Slavikova K, Biradar D, Khirsariya P, Vitek M, Sedlak D, Bartunek P, Daniel L, Brezovsky J, Damborsky J, Paruch K, Krejci L. Nikulenkov F, et al. Among authors: sisakova a. Eur J Med Chem. 2025 Jan 1;285:117226. doi: 10.1016/j.ejmech.2024.117226. Online ahead of print. Eur J Med Chem. 2025. PMID: 39793442
Srs2 promotes Mus81-Mms4-mediated resolution of recombination intermediates.
Chavdarova M, Marini V, Sisakova A, Sedlackova H, Vigasova D, Brill SJ, Lisby M, Krejci L. Chavdarova M, et al. Among authors: sisakova a. Nucleic Acids Res. 2015 Apr 20;43(7):3626-42. doi: 10.1093/nar/gkv198. Epub 2015 Mar 12. Nucleic Acids Res. 2015. PMID: 25765656 Free PMC article.
Srs2 mediates PCNA-SUMO-dependent inhibition of DNA repair synthesis.
Burkovics P, Sebesta M, Sisakova A, Plault N, Szukacsov V, Robert T, Pinter L, Marini V, Kolesar P, Haracska L, Gangloff S, Krejci L. Burkovics P, et al. Among authors: sisakova a. EMBO J. 2013 Mar 6;32(5):742-55. doi: 10.1038/emboj.2013.9. Epub 2013 Feb 8. EMBO J. 2013. PMID: 23395907 Free PMC article.
Cooperativity of Mus81.Mms4 with Rad54 in the resolution of recombination and replication intermediates.
Matulova P, Marini V, Burgess RC, Sisakova A, Kwon Y, Rothstein R, Sung P, Krejci L. Matulova P, et al. Among authors: sisakova a. J Biol Chem. 2009 Mar 20;284(12):7733-45. doi: 10.1074/jbc.M806192200. Epub 2009 Jan 7. J Biol Chem. 2009. Retraction in: J Biol Chem. 2024 Oct;300(10):107747. doi: 10.1016/j.jbc.2024.107747 PMID: 19129197 Free PMC article. Retracted.