FDW028, a novel FUT8 inhibitor, impels lysosomal proteolysis of B7-H3 via chaperone-mediated autophagy pathway and exhibits potent efficacy against metastatic colorectal cancer.
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Cell Death Dis. 2023 Aug 3;14(8):495. doi: 10.1038/s41419-023-06027-0.
Cell Death Dis. 2023.
PMID: 37537172
Free PMC article.