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222 results

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Page 1
Nivolumab combination therapies in patients with advanced gastric and gastroesophageal junction cancer: the phase II FRACTION gastric cancer study.
Ku G, Haag GM, Park H, Lam VK, George TJ, Kim SS, Gutierrez M, Shankaran V, Stein S, Denlinger CS, Elimova E, Nagrial A, He AR, Sawyer MB, Yoon HH, Geva R, Starr J, Curigliano G, Golan T, von Moos R, Fritsch R, Lim D, Wang Q, Patel A, Aoyama T, Lei M, Greenawalt D, Di Bartolomeo M. Ku G, et al. Among authors: golan t. ESMO Open. 2025 Jan 10;10(2):104107. doi: 10.1016/j.esmoop.2024.104107. Online ahead of print. ESMO Open. 2025. PMID: 39798422
First-in-human phase 1 dose-escalation results with livmoniplimab, an antibody targeting the GARP:TGF-ß1 complex, as monotherapy and in combination with the anti-PD-1 antibody budigalimab in patients with advanced solid tumors.
Shimizu T, Powderly J, Abdul Razak A, LoRusso P, Miller KD, Kao S, Kongpachith S, Tribouley C, Graham M, Stoll B, Patel M, Sahtout M, Blaney M, Leibman R, Golan T, Tolcher A. Shimizu T, et al. Among authors: golan t. Front Oncol. 2024 Oct 29;14:1376551. doi: 10.3389/fonc.2024.1376551. eCollection 2024. Front Oncol. 2024. PMID: 39534099 Free PMC article.
Transcatheter Valve Replacement in Severe Tricuspid Regurgitation.
Hahn RT, Makkar R, Thourani VH, Makar M, Sharma RP, Haeffele C, Davidson CJ, Narang A, O'Neill B, Lee J, Yadav P, Zahr F, Chadderdon S, Eleid M, Pislaru S, Smith R, Szerlip M, Whisenant B, Sekaran NK, Garcia S, Stewart-Dehner T, Thiele H, Kipperman R, Koulogiannis K, Lim DS, Fowler D, Kapadia S, Harb SC, Grayburn PA, Sannino A, Mack MJ, Leon MB, Lurz P, Kodali SK; TRISCEND II Trial Investigators. Hahn RT, et al. N Engl J Med. 2025 Jan 9;392(2):115-126. doi: 10.1056/NEJMoa2401918. Epub 2024 Oct 30. N Engl J Med. 2025. PMID: 39475399 Clinical Trial.
Crosslinking of Ly6a metabolically reprograms CD8 T cells for cancer immunotherapy.
Maliah A, Santana-Magal N, Parikh S, Gordon S, Reshef K, Sade Y, Khateeb A, Richter A, Gutwillig A, Parikh R, Golan T, Krissi M, Na M, Binshtok G, Manich P, Elkoshi N, Grisaru-Tal S, Zemser-Werner V, Brenner R, Vaknine H, Nizri E, Moyal L, Amitay-Laish I, Rosemberg L, Munitz A, Kronfeld-Schor N, Shifrut E, Kobiler O, Madi A, Geiger T, Carmi Y, Levy C. Maliah A, et al. Among authors: golan t. Nat Commun. 2024 Sep 27;15(1):8354. doi: 10.1038/s41467-024-52079-x. Nat Commun. 2024. PMID: 39333093 Free PMC article.
Serum matrix metalloproteinase-7, Syndecan-1, and CA 19-9 as a biomarker panel for diagnosis of pancreatic ductal adenocarcinoma.
Yablecovitch D, Nadler M, Ben-Horin S, Picard O, Yavzori M, Fudim E, Duchan MT, Sakhnini E, Lang A, Lahav M, Saker T, Neuman S, Selinger L, Freitz B, Dvir R, Raitses-Gurevich M, Golan T, Levy I, Laish I. Yablecovitch D, et al. Among authors: golan t. Cancer Med. 2024 Sep;13(17):e70144. doi: 10.1002/cam4.70144. Cancer Med. 2024. PMID: 39263943 Free PMC article.
Human aneuploid cells depend on the RAF/MEK/ERK pathway for overcoming increased DNA damage.
Zerbib J, Ippolito MR, Eliezer Y, De Feudis G, Reuveni E, Savir Kadmon A, Martin S, Viganò S, Leor G, Berstler J, Muenzner J, Mülleder M, Campagnolo EM, Shulman ED, Chang T, Rubolino C, Laue K, Cohen-Sharir Y, Scorzoni S, Taglietti S, Ratti A, Stossel C, Golan T, Nicassio F, Ruppin E, Ralser M, Vazquez F, Ben-David U, Santaguida S. Zerbib J, et al. Among authors: golan t. Nat Commun. 2024 Sep 9;15(1):7772. doi: 10.1038/s41467-024-52176-x. Nat Commun. 2024. PMID: 39251587 Free PMC article.
Devimistat (CPI-613) With Modified Fluorouarcil, Oxaliplatin, Irinotecan, and Leucovorin (FFX) Versus FFX for Patients With Metastatic Adenocarcinoma of the Pancreas: The Phase III AVENGER 500 Study.
Philip PA, Sahai V, Bahary N, Mahipal A, Kasi A, Rocha Lima CMS, Alistar AT, Oberstein PE, Golan T, Metges JP, Lacy J, Fountzilas C, Lopez CD, Ducreux M, Hammel P, Salem M, Bajor D, Benson AB, Luther S, Pardee T, Van Cutsem E. Philip PA, et al. Among authors: golan t. J Clin Oncol. 2024 Nov;42(31):3692-3701. doi: 10.1200/JCO.23.02659. Epub 2024 Aug 1. J Clin Oncol. 2024. PMID: 39088774 Clinical Trial.
Senescent cancer-associated fibroblasts in pancreatic adenocarcinoma restrict CD8+ T cell activation and limit responsiveness to immunotherapy in mice.
Assouline B, Kahn R, Hodali L, Condiotti R, Engel Y, Elyada E, Mordechai-Heyn T, Pitarresi JR, Atias D, Steinberg E, Bidany-Mizrahi T, Forkosh E, Katz LH, Benny O, Golan T, Hofree M, Stewart SA, Atlan KA, Zamir G, Stanger BZ, Berger M, Ben-Porath I. Assouline B, et al. Among authors: golan t. Nat Commun. 2024 Jul 22;15(1):6162. doi: 10.1038/s41467-024-50441-7. Nat Commun. 2024. PMID: 39039076 Free PMC article.
222 results