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115 results

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Genomic and transcriptomic profiling of radioresistant prostate and head and neck cancers implicate a BAHD1-dependent modification of DNA damage at the heterochromatin.
Beh CY, Yeo CPX, Hong BH, Tan EMC, Tan KM, Poon DJJ, Chu PL, Susanti D, Tai PL, Ryu M, Proudfoot J, Yeo ELL, Soo KC, Chua MLK. Beh CY, et al. Among authors: chu pl. Cell Death Dis. 2024 Dec 24;15(12):929. doi: 10.1038/s41419-024-07316-y. Cell Death Dis. 2024. PMID: 39719436 Free PMC article.
Vandetanib sensitizes head and neck squamous cell carcinoma to photodynamic therapy through modulation of EGFR-dependent DNA repair and the tumour microenvironment.
Chu PL, Shihabuddeen WA, Low KP, Poon DJJ, Ramaswamy B, Liang ZG, Nei WL, Chua KLM, Thong PSP, Soo KC, Yeo ELL, Chua MLK. Chu PL, et al. Photodiagnosis Photodyn Ther. 2019 Sep;27:367-374. doi: 10.1016/j.pdpdt.2019.06.008. Epub 2019 Jul 9. Photodiagnosis Photodyn Ther. 2019. PMID: 31299389 Free article.
The Proteogenomics of Prostate Cancer Radioresistance.
Haas R, Frame G, Khan S, Neilsen BK, Hong BH, Yeo CPX, Yamaguchi TN, Ong EHW, Zhao W, Carlin B, Yeo ELL, Tan KM, Bugh YZ, Zhu C, Hugh-White R, Livingstone J, Poon DJJ, Chu PL, Patel Y, Tao S, Ignatchenko V, Kurganovs NJ, Higgins GS, Downes MR, Loblaw A, Vesprini D, Kishan AU, Chua MLK, Kislinger T, Boutros PC, Liu SK. Haas R, et al. Among authors: chu pl. Cancer Res Commun. 2024 Sep 1;4(9):2463-2479. doi: 10.1158/2767-9764.CRC-24-0292. Cancer Res Commun. 2024. PMID: 39166898 Free PMC article.
High-Dimensional Characterization of the Systemic Immune Landscape Informs on Synergism Between Radiation Therapy and Immune Checkpoint Blockade.
Chua KLM, Fehlings M, Yeo ELL, Nardin A, Sumatoh H, Chu PL, Nei WL, Ong EHW, Woo WY, Low KP, Wang H, Poon DJJ, Liang ZG, Yao K, Huang L, Toh CK, Ang MK, Farid M, Cheng XM, Kanesvaran R, Dent R, Wee JTS, Lim TKH, Iyer NG, Tan DSW, Soo KC, Newell EW, Chua MLK. Chua KLM, et al. Among authors: chu pl. Int J Radiat Oncol Biol Phys. 2020 Sep 1;108(1):70-80. doi: 10.1016/j.ijrobp.2020.06.007. Epub 2020 Jun 13. Int J Radiat Oncol Biol Phys. 2020. PMID: 32544576 Free article.
Cholangiocarcinoma: Recent Advances in Molecular Pathobiology and Therapeutic Approaches.
Khosla D, Misra S, Chu PL, Guan P, Nada R, Gupta R, Kaewnarin K, Ko TK, Heng HL, Srinivasalu VK, Kapoor R, Singh D, Klanrit P, Sampattavanich S, Tan J, Kongpetch S, Jusakul A, Teh BT, Chan JY, Hong JH. Khosla D, et al. Among authors: chu pl. Cancers (Basel). 2024 Feb 16;16(4):801. doi: 10.3390/cancers16040801. Cancers (Basel). 2024. PMID: 38398194 Free PMC article. Review.
Integrative multiomics enhancer activity profiling identifies therapeutic vulnerabilities in cholangiocarcinoma of different etiologies.
Hong JH, Yong CH, Heng HL, Chan JY, Lau MC, Chen J, Lee JY, Lim AH, Li Z, Guan P, Chu PL, Boot A, Ng SR, Yao X, Wee FYT, Lim JCT, Liu W, Wang P, Xiao R, Zeng X, Sun Y, Koh J, Kwek XY, Ng CCY, Klanrit P, Zhang Y, Lai J, Tai DWM, Pairojkul C, Dima S, Popescu I, Hsieh SY, Yu MC, Yeong J, Kongpetch S, Jusakul A, Loilome W, Tan P, Tan J, Teh BT. Hong JH, et al. Among authors: chu pl. Gut. 2024 May 10;73(6):966-984. doi: 10.1136/gutjnl-2023-330483. Gut. 2024. PMID: 38050079
Upconversion superballs for programmable photoactivation of therapeutics.
Zhang Z, Jayakumar MKG, Zheng X, Shikha S, Zhang Y, Bansal A, Poon DJJ, Chu PL, Yeo ELL, Chua MLK, Chee SK, Zhang Y. Zhang Z, et al. Among authors: chu pl. Nat Commun. 2019 Oct 8;10(1):4586. doi: 10.1038/s41467-019-12506-w. Nat Commun. 2019. PMID: 31594932 Free PMC article.
PBRM1-deficient PBAF complexes target aberrant genomic loci to activate the NF-κB pathway in clear cell renal cell carcinoma.
Yao X, Hong JH, Nargund AM, Ng MSW, Heng HL, Li Z, Guan P, Sugiura M, Chu PL, Wang LC, Ye X, Qu J, Kwek XY, Lim JCT, Ooi WF, Koh J, Wang Z, Pan YF, Ong YS, Tan KY, Goh JY, Ng SR, Pignata L, Huang D, Lezhava A, Tay ST, Lee M, Yeo XH, Tam WL, Rha SY, Li S, Guccione E, Futreal A, Tan J, Yeong JPS, Hong W, Yauch R, Chang KT, Sobota RM, Tan P, Teh BT. Yao X, et al. Among authors: chu pl. Nat Cell Biol. 2023 May;25(5):765-777. doi: 10.1038/s41556-023-01122-y. Epub 2023 Apr 24. Nat Cell Biol. 2023. PMID: 37095322
115 results