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Page 1
Pathobiont-triggered induction of epithelial IDO1 drives regional susceptibility to Inflammatory Bowel Disease.
Spencer PN, Wang J, Smith EP, Spiga L, Simmons AJ, Kim T, Kim W, Brown ME, Yang Y, Kaur H, Xu Y, Kang SW, Helou MD, Lee MA, Zheng L, Arceneaux D, Tasneem N, Mueller KD, Kuddar OS, Harned MH, Ro J, Li J, Banerjee A, Markham NO, Wilson KT, Coburn LA, Goettel JA, Liu Q, Washington MK, Valdivia RH, Zhu W, Lau KS. Spencer PN, et al. Among authors: markham no. bioRxiv [Preprint]. 2025 Jan 4:2025.01.04.630951. doi: 10.1101/2025.01.04.630951. bioRxiv. 2025. PMID: 39803424 Free PMC article. Preprint.
IL-17 signaling protects against Helicobacter pylori-induced gastric cancer.
Brackman LC, Jung MS, Green EH, Joshi N, Revetta FL, McClain MS, Markham NO, Piazuelo MB, Scott Algood HM. Brackman LC, et al. Among authors: markham no. Gut Microbes. 2024 Jan-Dec;16(1):2430421. doi: 10.1080/19490976.2024.2430421. Epub 2024 Nov 26. Gut Microbes. 2024. PMID: 39588838 Free PMC article.
Inhibition of EGFR/ErbB does not protect against C. difficile toxin B.
Siddiqi U, Lunnemann HM, Childress KO, Shupe JA, Rutherford SA, Farrow MA, Washington MK, Coffey RJ, Lacy DB, Markham NO. Siddiqi U, et al. Among authors: markham no. bioRxiv [Preprint]. 2024 May 14:2024.05.13.594035. doi: 10.1101/2024.05.13.594035. bioRxiv. 2024. PMID: 38798529 Free PMC article. Preprint.
Molecular cartography uncovers evolutionary and microenvironmental dynamics in sporadic colorectal tumors.
Heiser CN, Simmons AJ, Revetta F, McKinley ET, Ramirez-Solano MA, Wang J, Kaur H, Shao J, Ayers GD, Wang Y, Glass SE, Tasneem N, Chen Z, Qin Y, Kim W, Rolong A, Chen B, Vega PN, Drewes JL, Markham NO, Saleh N, Nikolos F, Vandekar S, Jones AL, Washington MK, Roland JT, Chan KS, Schürpf T, Sears CL, Liu Q, Shrubsole MJ, Coffey RJ, Lau KS. Heiser CN, et al. Among authors: markham no. Cell. 2023 Dec 7;186(25):5620-5637.e16. doi: 10.1016/j.cell.2023.11.006. Cell. 2023. PMID: 38065082 Free PMC article.
An early-life microbiota metabolite protects against obesity by regulating intestinal lipid metabolism.
Shelton CD, Sing E, Mo J, Shealy NG, Yoo W, Thomas J, Fitz GN, Castro PR, Hickman TT, Torres TP, Foegeding NJ, Zieba JK, Calcutt MW, Codreanu SG, Sherrod SD, McLean JA, Peck SH, Yang F, Markham NO, Liu M, Byndloss MX. Shelton CD, et al. Among authors: markham no. Cell Host Microbe. 2023 Oct 11;31(10):1604-1619.e10. doi: 10.1016/j.chom.2023.09.002. Epub 2023 Oct 3. Cell Host Microbe. 2023. PMID: 37794592 Free PMC article.
Human Colon Cancer-Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice.
Drewes JL, Chen J, Markham NO, Knippel RJ, Domingue JC, Tam AJ, Chan JL, Kim L, McMann M, Stevens C, Dejea CM, Tomkovich S, Michel J, White JR, Mohammad F, Campodónico VL, Heiser CN, Wu X, Wu S, Ding H, Simner P, Carroll K, Shrubsole MJ, Anders RA, Walk ST, Jobin C, Wan F, Coffey RJ, Housseau F, Lau KS, Sears CL. Drewes JL, et al. Among authors: markham no. Cancer Discov. 2022 Aug 5;12(8):1873-1885. doi: 10.1158/2159-8290.CD-21-1273. Cancer Discov. 2022. PMID: 35678528 Free PMC article.
Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps.
Chen B, Scurrah CR, McKinley ET, Simmons AJ, Ramirez-Solano MA, Zhu X, Markham NO, Heiser CN, Vega PN, Rolong A, Kim H, Sheng Q, Drewes JL, Zhou Y, Southard-Smith AN, Xu Y, Ro J, Jones AL, Revetta F, Berry LD, Niitsu H, Islam M, Pelka K, Hofree M, Chen JH, Sarkizova S, Ng K, Giannakis M, Boland GM, Aguirre AJ, Anderson AC, Rozenblatt-Rosen O, Regev A, Hacohen N, Kawasaki K, Sato T, Goettel JA, Grady WM, Zheng W, Washington MK, Cai Q, Sears CL, Goldenring JR, Franklin JL, Su T, Huh WJ, Vandekar S, Roland JT, Liu Q, Coffey RJ, Shrubsole MJ, Lau KS. Chen B, et al. Among authors: markham no. Cell. 2021 Dec 22;184(26):6262-6280.e26. doi: 10.1016/j.cell.2021.11.031. Epub 2021 Dec 14. Cell. 2021. PMID: 34910928 Free PMC article.
Fecal Microbiota Transplantation for Recurrent Clostridioides difficile Infection Associates With Functional Alterations in Circulating microRNAs.
Monaghan TM, Seekatz AM, Markham NO, Yau TO, Hatziapostolou M, Jilani T, Christodoulou N, Roach B, Birli E, Pomenya O, Louie T, Lacy DB, Kim P, Lee C, Kao D, Polytarchou C. Monaghan TM, et al. Among authors: markham no. Gastroenterology. 2021 Jul;161(1):255-270.e4. doi: 10.1053/j.gastro.2021.03.050. Epub 2021 Apr 9. Gastroenterology. 2021. PMID: 33844988 Free PMC article.
21 results