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Page 1
Pathobiont-triggered induction of epithelial IDO1 drives regional susceptibility to Inflammatory Bowel Disease.
Spencer PN, Wang J, Smith EP, Spiga L, Simmons AJ, Kim T, Kim W, Brown ME, Yang Y, Kaur H, Xu Y, Kang SW, Helou MD, Lee MA, Zheng L, Arceneaux D, Tasneem N, Mueller KD, Kuddar OS, Harned MH, Ro J, Li J, Banerjee A, Markham NO, Wilson KT, Coburn LA, Goettel JA, Liu Q, Washington MK, Valdivia RH, Zhu W, Lau KS. Spencer PN, et al. Among authors: simmons aj. bioRxiv [Preprint]. 2025 Jan 4:2025.01.04.630951. doi: 10.1101/2025.01.04.630951. bioRxiv. 2025. PMID: 39803424 Free PMC article. Preprint.
Temporal recording of mammalian development and precancer.
Islam M, Yang Y, Simmons AJ, Shah VM, Musale KP, Xu Y, Tasneem N, Chen Z, Trinh LT, Molina P, Ramirez-Solano MA, Sadien ID, Dou J, Rolong A, Chen K, Magnuson MA, Rathmell JC, Macara IG, Winton DJ, Liu Q, Zafar H, Kalhor R, Church GM, Shrubsole MJ, Coffey RJ, Lau KS. Islam M, et al. Among authors: simmons aj. Nature. 2024 Oct;634(8036):1187-1195. doi: 10.1038/s41586-024-07954-4. Epub 2024 Oct 30. Nature. 2024. PMID: 39478207 Free PMC article.
Biofunctionalized gelatin hydrogels support development and maturation of iPSC-derived cortical organoids.
Kjar A, Haschert MR, Zepeda JC, Simmons AJ, Yates A, Chavarria D, Fernandez M, Robertson G, Abdulrahman AM, Kim H, Marguerite NT, Moen RK, Drake LE, Curry CW, O'Grady BJ, Gama V, Lau KS, Grueter B, Brunger JM, Lippmann ES. Kjar A, et al. Among authors: simmons aj. Cell Rep. 2024 Nov 26;43(11):114874. doi: 10.1016/j.celrep.2024.114874. Epub 2024 Oct 17. Cell Rep. 2024. PMID: 39423129 Free PMC article.
Identification and multimodal characterization of a specialized epithelial cell type associated with Crohn's disease.
Li J, Simmons AJ, Hawkins CV, Chiron S, Ramirez-Solano MA, Tasneem N, Kaur H, Xu Y, Revetta F, Vega PN, Bao S, Cui C, Tyree RN, Raber LW, Conner AN, Pilat JM, Jacobse J, McNamara KM, Allaman MM, Raffa GA, Gobert AP, Asim M, Goettel JA, Choksi YA, Beaulieu DB, Dalal RL, Horst SN, Pabla BS, Huo Y, Landman BA, Roland JT, Scoville EA, Schwartz DA, Washington MK, Shyr Y, Wilson KT, Coburn LA, Lau KS, Liu Q. Li J, et al. Among authors: simmons aj. Nat Commun. 2024 Aug 22;15(1):7204. doi: 10.1038/s41467-024-51580-7. Nat Commun. 2024. PMID: 39169060 Free PMC article.
MTGR1 is required to maintain small intestinal stem cell populations.
Short SP, Brown RE, Chen Z, Pilat JM, McElligott BA, Meenderink LM, Bickart AC, Blunt KM, Jacobse J, Wang J, Simmons AJ, Xu Y, Yang Y, Parang B, Choksi YA, Goettel JA, Lau KS, Hiebert SW, Williams CS. Short SP, et al. Among authors: simmons aj. Cell Death Differ. 2024 Sep;31(9):1170-1183. doi: 10.1038/s41418-024-01346-x. Epub 2024 Jul 25. Cell Death Differ. 2024. PMID: 39048708 Free PMC article.
Interleukin 13 Promotes Maturation and Proliferation in Metaplastic Gastroids.
Contreras-Panta EW, Lee SH, Won Y, Norlander AE, Simmons AJ, Peebles RS Jr, Lau KS, Choi E, Goldenring JR. Contreras-Panta EW, et al. Among authors: simmons aj. Cell Mol Gastroenterol Hepatol. 2024;18(3):101366. doi: 10.1016/j.jcmgh.2024.101366. Epub 2024 May 29. Cell Mol Gastroenterol Hepatol. 2024. PMID: 38815928 Free PMC article.
Temporal recording of mammalian development and precancer.
Islam M, Yang Y, Simmons AJ, Shah VM, Pavan MK, Xu Y, Tasneem N, Chen Z, Trinh LT, Molina P, Ramirez-Solano MA, Sadien I, Dou J, Chen K, Magnuson MA, Rathmell JC, Macara IG, Winton D, Liu Q, Zafar H, Kalhor R, Church GM, Shrubsole MJ, Coffey RJ, Lau KS. Islam M, et al. Among authors: simmons aj. bioRxiv [Preprint]. 2023 Dec 19:2023.12.18.572260. doi: 10.1101/2023.12.18.572260. bioRxiv. 2023. Update in: Nature. 2024 Oct;634(8036):1187-1195. doi: 10.1038/s41586-024-07954-4 PMID: 38187699 Free PMC article. Updated. Preprint.
Molecular cartography uncovers evolutionary and microenvironmental dynamics in sporadic colorectal tumors.
Heiser CN, Simmons AJ, Revetta F, McKinley ET, Ramirez-Solano MA, Wang J, Kaur H, Shao J, Ayers GD, Wang Y, Glass SE, Tasneem N, Chen Z, Qin Y, Kim W, Rolong A, Chen B, Vega PN, Drewes JL, Markham NO, Saleh N, Nikolos F, Vandekar S, Jones AL, Washington MK, Roland JT, Chan KS, Schürpf T, Sears CL, Liu Q, Shrubsole MJ, Coffey RJ, Lau KS. Heiser CN, et al. Among authors: simmons aj. Cell. 2023 Dec 7;186(25):5620-5637.e16. doi: 10.1016/j.cell.2023.11.006. Cell. 2023. PMID: 38065082 Free PMC article.
49 results