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Page 1
Multiplex genome editing eliminates lactate production without impacting growth rate in mammalian cells.
Hefzi H, Martínez-Monge I, Marin de Mas I, Cowie NL, Toledo AG, Noh SM, Karottki KJC, Decker M, Arnsdorf J, Camacho-Zaragoza JM, Kol S, Schoffelen S, Pristovšek N, Hansen AH, Miguez AA, Bjørn SP, Brøndum KK, Javidi EM, Jensen KL, Stangl L, Kreidl E, Kallehauge TB, Ley D, Ménard P, Petersen HM, Sukhova Z, Bauer A, Casanova E, Barron N, Malmström J, Nielsen LK, Lee GM, Kildegaard HF, Voldborg BG, Lewis NE. Hefzi H, et al. Among authors: bjorn sp. Nat Metab. 2025 Jan 14. doi: 10.1038/s42255-024-01193-7. Online ahead of print. Nat Metab. 2025. PMID: 39809975
Multiplex genome editing eliminates the Warburg Effect without impacting growth rate in mammalian cells.
Hefzi H, Martínez-Monge I, Marin de Mas I, Cowie NL, Toledo AG, Noh SM, Karottki KJC, Decker M, Arnsdorf J, Camacho-Zaragoza JM, Kol S, Schoffelen S, Pristovšek N, Hansen AH, Miguez AA, Bjorn SP, Brøndum KK, Javidi EM, Jensen KL, Stangl L, Kreidl E, Kallehauge TB, Ley D, Ménard P, Petersen HM, Sukhova Z, Bauer A, Casanova E, Barron N, Malmström J, Nielsen LK, Lee GM, Kildegaard HF, Voldborg BG, Lewis NE. Hefzi H, et al. Among authors: bjorn sp. bioRxiv [Preprint]. 2024 Aug 6:2024.08.02.606284. doi: 10.1101/2024.08.02.606284. bioRxiv. 2024. Update in: Nat Metab. 2025 Jan 14. doi: 10.1038/s42255-024-01193-7 PMID: 39211256 Free PMC article. Updated. Preprint.
In vivo neutralization of coral snake venoms with an oligoclonal nanobody mixture in a murine challenge model.
Benard-Valle M, Wouters Y, Ljungars A, Nguyen GTT, Ahmadi S, Ebersole TW, Dahl CH, Guadarrama-Martínez A, Jeppesen F, Eriksen H, Rodríguez-Barrera G, Boddum K, Jenkins TP, Bjørn SP, Schoffelen S, Voldborg BG, Alagón A, Laustsen AH. Benard-Valle M, et al. Among authors: bjorn sp. Nat Commun. 2024 May 21;15(1):4310. doi: 10.1038/s41467-024-48539-z. Nat Commun. 2024. PMID: 38773068 Free PMC article.
Glycoengineered recombinant alpha1-antitrypsin results in comparable in vitro and in vivo activities to human plasma-derived protein.
Rocamora F, Schoffelen S, Arnsdorf J, Toth EA, Abdul Y, Cleveland TE 4th, Bjørn SP, Wu MYM, McElvaney NG, Voldborg BGR, Fuerst TR, Lewis NE. Rocamora F, et al. Among authors: bjorn sp. bioRxiv [Preprint]. 2024 Mar 30:2024.03.27.587088. doi: 10.1101/2024.03.27.587088. bioRxiv. 2024. PMID: 38585818 Free PMC article. Preprint.
Highly Selective Lysine Acylation in Proteins Using a Lys-His Tag Sequence.
Kofoed C, Wu S, Sørensen KK, Treiberg T, Arnsdorf J, Bjørn SP, Jensen TL, Voldborg BG, Thygesen MB, Jensen KJ, Schoffelen S. Kofoed C, et al. Among authors: bjorn sp. Chemistry. 2022 Mar 10;28(15):e202200147. doi: 10.1002/chem.202200147. Epub 2022 Feb 17. Chemistry. 2022. PMID: 35099088
Evolution-guided engineering of small-molecule biosensors.
Snoek T, Chaberski EK, Ambri F, Kol S, Bjørn SP, Pang B, Barajas JF, Welner DH, Jensen MK, Keasling JD. Snoek T, et al. Among authors: bjorn sp. Nucleic Acids Res. 2020 Jan 10;48(1):e3. doi: 10.1093/nar/gkz954. Nucleic Acids Res. 2020. PMID: 31777933 Free PMC article.
Combating viral contaminants in CHO cells by engineering innate immunity.
Chiang AWT, Li S, Kellman BP, Chattopadhyay G, Zhang Y, Kuo CC, Gutierrez JM, Ghazi F, Schmeisser H, Ménard P, Bjørn SP, Voldborg BG, Rosenberg AS, Puig M, Lewis NE. Chiang AWT, et al. Among authors: bjorn sp. Sci Rep. 2019 Jun 20;9(1):8827. doi: 10.1038/s41598-019-45126-x. Sci Rep. 2019. PMID: 31222165 Free PMC article.
17 results