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Small molecules targeting selective PCK1 and PGC-1α lysine acetylation cause anti-diabetic action through increased lactate oxidation.
Mutlu B, Sharabi K, Sohn JH, Yuan B, Latorre-Muro P, Qin X, Yook JS, Lin H, Yu D, Camporez JPG, Kajimura S, Shulman GI, Hui S, Kamenecka TM, Griffin PR, Puigserver P. Mutlu B, et al. Among authors: latorre muro p. Cell Chem Biol. 2025 Jan 14:S2451-9456(25)00005-4. doi: 10.1016/j.chembiol.2025.01.005. Online ahead of print. Cell Chem Biol. 2025. PMID: 39814023 No abstract available.
Absence of MCJ/DnaJC15 promotes brown adipose tissue thermogenesis.
Cicuéndez B, Mora A, López JA, Curtabbi A, Pérez-García J, Porteiro B, Jimenez-Blasco D, Latorre-Muro P, Vo P, Jerome M, Gómez-Santos B, Romero-Becerra R, Leiva M, Rodríguez E, León M, Leiva-Vega L, Gómez-Lado N, Torres JL, Hernández-Cosido L, Aguiar P, Marcos M, Jastroch M, Daiber A, Aspichueta P, Bolaños JP, Spinelli JB, Puigserver P, Enriquez JA, Vázquez J, Folgueira C, Sabio G. Cicuéndez B, et al. Among authors: latorre muro p. Nat Commun. 2025 Jan 13;16(1):229. doi: 10.1038/s41467-024-54353-4. Nat Commun. 2025. PMID: 39805849 Free PMC article.
The human zinc-binding cysteine proteome.
Burger N, Mittenbühler MJ, Xiao H, Shin S, Wei SM, Henze EK, Schindler S, Mehravar S, Wood DM, Petrocelli JJ, Sun Y, Sprenger HG, Latorre-Muro P, Smythers AL, Bozi LHM, Darabedian N, Zhu Y, Seo HS, Dhe-Paganon S, Che J, Chouchani ET. Burger N, et al. Among authors: latorre muro p. Cell. 2024 Dec 26:S0092-8674(24)01341-2. doi: 10.1016/j.cell.2024.11.025. Online ahead of print. Cell. 2024. PMID: 39742810 Free article.
Structural basis of respiratory complex adaptation to cold temperatures.
Shin YC, Latorre-Muro P, Djurabekova A, Zdorevskyi O, Bennett CF, Burger N, Song K, Xu C, Paulo JA, Gygi SP, Sharma V, Liao M, Puigserver P. Shin YC, et al. Among authors: latorre muro p. Cell. 2024 Nov 14;187(23):6584-6598.e17. doi: 10.1016/j.cell.2024.09.029. Epub 2024 Oct 11. Cell. 2024. PMID: 39395414
Small molecules targeting selective PCK1 and PGC-1α lysine acetylation cause anti-diabetic action through increased lactate oxidation.
Mutlu B, Sharabi K, Sohn JH, Yuan B, Latorre-Muro P, Qin X, Yook JS, Lin H, Yu D, Camporez JPG, Kajimura S, Shulman GI, Hui S, Kamenecka TM, Griffin PR, Puigserver P. Mutlu B, et al. Among authors: latorre muro p. Cell Chem Biol. 2024 Oct 17;31(10):1772-1786.e5. doi: 10.1016/j.chembiol.2024.09.001. Epub 2024 Sep 27. Cell Chem Biol. 2024. PMID: 39341205
Structural basis of respiratory complexes adaptation to cold temperatures.
Shin YC, Latorre-Muro P, Djurabekova A, Zdorevskyi O, Bennett CF, Burger N, Song K, Xu C, Sharma V, Liao M, Puigserver P. Shin YC, et al. Among authors: latorre muro p. bioRxiv [Preprint]. 2024 Jan 17:2024.01.16.575914. doi: 10.1101/2024.01.16.575914. bioRxiv. 2024. Update in: Cell. 2024 Nov 14;187(23):6584-6598.e17. doi: 10.1016/j.cell.2024.09.029 PMID: 38293190 Free PMC article. Updated. Preprint.
Liver mitochondrial cristae organizing protein MIC19 promotes energy expenditure and pedestrian locomotion by altering nucleotide metabolism.
Sohn JH, Mutlu B, Latorre-Muro P, Liang J, Bennett CF, Sharabi K, Kantorovich N, Jedrychowski M, Gygi SP, Banks AS, Puigserver P. Sohn JH, et al. Among authors: latorre muro p. Cell Metab. 2023 Aug 8;35(8):1356-1372.e5. doi: 10.1016/j.cmet.2023.06.015. Epub 2023 Jul 19. Cell Metab. 2023. PMID: 37473754 Free PMC article.
17 results