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The human and non-human primate developmental GTEx projects.
Coorens THH, Guillaumet-Adkins A, Kovner R, Linn RL, Roberts VHJ, Sule A, Van Hoose PM; dGTEx Consortium. Coorens THH, et al. Nature. 2025 Jan;637(8046):557-564. doi: 10.1038/s41586-024-08244-9. Epub 2025 Jan 15. Nature. 2025. PMID: 39815096 Review.
Prolonged persistence of mutagenic DNA lesions in somatic cells.
Spencer Chapman M, Mitchell E, Yoshida K, Williams N, Fabre MA, Ranzoni AM, Robinson PS, Kregar LD, Wilk M, Boettcher S, Mahbubani K, Saeb Parsy K, Gowers KHC, Janes SM, Ng SWK, Hoare M, Green AR, Vassiliou GS, Cvejic A, Manz MG, Laurenti E, Martincorena I, Stratton MR, Nangalia J, Coorens THH, Campbell PJ. Spencer Chapman M, et al. Among authors: coorens thh. Nature. 2025 Jan 15. doi: 10.1038/s41586-024-08423-8. Online ahead of print. Nature. 2025. PMID: 39814886
Predisposition footprints in the somatic genome of Wilms tumours.
Treger TD, Wegert J, Wenger A, Coorens THH, Al-Saadi R, Kemps PG, Kennedy J, Parks C, Anderson ND, Hodder A, Letunovska A, Jung H, Ogbonnah T, Trinh MK, Lee-Six H, Morcrette G, van den Heuvel-Eibrink MM, Drost J, van Boxtel R, Bertrums EJM, Goemans BF, Antoniou E, Reinhardt D, Streitenberger H, Ziegler B, Bartram J, Hutchinson JC, Vujanic GM, Vokuhl C, Chowdhury T, Furtwängler R, Graf N, Pritchard-Jones K, Gessler M, Behjati S. Treger TD, et al. Among authors: coorens thh. Cancer Discov. 2024 Dec 12:10.1158/2159-8290.CD-24-0878. doi: 10.1158/2159-8290.CD-24-0878. Online ahead of print. Cancer Discov. 2024. PMID: 39665570 Free PMC article.
Single-cell multi-omics map of human fetal blood in Down syndrome.
Marderstein AR, De Zuani M, Moeller R, Bezney J, Padhi EM, Wong S, Coorens THH, Xie Y, Xue H, Montgomery SB, Cvejic A. Marderstein AR, et al. Among authors: coorens thh. Nature. 2024 Oct;634(8032):104-112. doi: 10.1038/s41586-024-07946-4. Epub 2024 Sep 25. Nature. 2024. PMID: 39322663 Free PMC article.
Genetic variation across and within individuals.
Yu Z, Coorens THH, Uddin MM, Ardlie KG, Lennon N, Natarajan P. Yu Z, et al. Among authors: coorens thh. Nat Rev Genet. 2024 Aug;25(8):548-562. doi: 10.1038/s41576-024-00709-x. Epub 2024 Mar 28. Nat Rev Genet. 2024. PMID: 38548833 Review.
Haplotype-specific assembly of shattered chromosomes in esophageal adenocarcinomas.
Ijaz J, Harry E, Raine K, Menzies A, Beal K, Quail MA, Zumalave S, Jung H, Coorens THH, Lawson ARJ, Leongamornlert D, Francies HE, Garnett MJ, Ning Z, Campbell PJ. Ijaz J, et al. Among authors: coorens thh. Cell Genom. 2024 Feb 14;4(2):100484. doi: 10.1016/j.xgen.2023.100484. Epub 2024 Jan 16. Cell Genom. 2024. PMID: 38232733 Free PMC article.
Targetable NOTCH1 rearrangements in reninoma.
Treger TD, Lawrence JEG, Anderson ND, Coorens THH, Letunovska A, Abby E, Lee-Six H, Oliver TRW, Al-Saadi R, Tullus K, Morcrette G, Hutchinson JC, Rampling D, Sebire N, Pritchard-Jones K, Young MD, Mitchell TJ, Jones PH, Tran M, Behjati S, Chowdhury T. Treger TD, et al. Among authors: coorens thh. Nat Commun. 2023 Sep 25;14(1):5826. doi: 10.1038/s41467-023-41118-8. Nat Commun. 2023. PMID: 37749094 Free PMC article.
Author Correction: Reliable detection of somatic mutations in solid tissues by laser-capture microdissection and low-input DNA sequencing.
Ellis P, Moore L, Sanders MA, Butler TM, Brunner SF, Lee-Six H, Osborne R, Farr B, Coorens THH, Lawson ARJ, Cagan A, Stratton MR, Martincorena I, Campbell PJ. Ellis P, et al. Among authors: coorens thh. Nat Protoc. 2023 Jun;18(6):1979. doi: 10.1038/s41596-023-00816-9. Nat Protoc. 2023. PMID: 36849600 No abstract available.
38 results