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Pellino 3 E3 ligase promotes starvation-induced autophagy to prevent hepatic steatosis.
Kolapalli SP, Beese CJ, Reid SE, Brynjólfsdóttir SH, Jørgensen MH, Jain A, Cuenco J, Lewinska M, Abdul-Al A, López AR, Jäättelä M, Sakamoto K, Andersen JB, Maeda K, Rusten TE, Lund AH, Frankel LB. Kolapalli SP, et al. Among authors: frankel lb. Sci Adv. 2025 Jan 17;11(3):eadr2450. doi: 10.1126/sciadv.adr2450. Epub 2025 Jan 17. Sci Adv. 2025. PMID: 39823344
Autophagy-mediated control of ribosome homeostasis in oncogene-induced senescence.
López AR, Jørgensen MH, Havelund JF, Arendrup FS, Kolapalli SP, Nielsen TM, Pais E, Beese CJ, Abdul-Al A, Vind AC, Bartek J, Bekker-Jensen S, Montes M, Galanos P, Faergeman N, Happonen L, Frankel LB. López AR, et al. Among authors: frankel lb. Cell Rep. 2023 Nov 28;42(11):113381. doi: 10.1016/j.celrep.2023.113381. Epub 2023 Nov 5. Cell Rep. 2023. PMID: 37930887 Free article.
Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response.
Snieckute G, Genzor AV, Vind AC, Ryder L, Stoneley M, Chamois S, Dreos R, Nordgaard C, Sass F, Blasius M, López AR, Brynjólfsdóttir SH, Andersen KL, Willis AE, Frankel LB, Poulsen SS, Gatfield D, Gerhart-Hines Z, Clemmensen C, Bekker-Jensen S. Snieckute G, et al. Among authors: frankel lb. Cell Metab. 2022 Dec 6;34(12):2036-2046.e8. doi: 10.1016/j.cmet.2022.10.011. Epub 2022 Nov 15. Cell Metab. 2022. PMID: 36384144 Free PMC article.
Measuring Autophagic Cargo Flux with Keima-Based Probes.
Engedal N, Sønstevold T, Beese CJ, Selladurai S, Melcher T, Simensen JE, Frankel LB, Urbanucci A, Torgersen ML. Engedal N, et al. Among authors: frankel lb. Methods Mol Biol. 2022;2445:99-115. doi: 10.1007/978-1-0716-2071-7_7. Methods Mol Biol. 2022. PMID: 34972988
Spatial-proteomics reveals phospho-signaling dynamics at subcellular resolution.
Martinez-Val A, Bekker-Jensen DB, Steigerwald S, Koenig C, Østergaard O, Mehta A, Tran T, Sikorski K, Torres-Vega E, Kwasniewicz E, Brynjólfsdóttir SH, Frankel LB, Kjøbsted R, Krogh N, Lundby A, Bekker-Jensen S, Lund-Johansen F, Olsen JV. Martinez-Val A, et al. Among authors: frankel lb. Nat Commun. 2021 Dec 7;12(1):7113. doi: 10.1038/s41467-021-27398-y. Nat Commun. 2021. PMID: 34876567 Free PMC article.
EIF4A3: a gatekeeper of autophagy.
Sakellariou D, Frankel LB. Sakellariou D, et al. Among authors: frankel lb. Autophagy. 2021 Dec;17(12):4504-4505. doi: 10.1080/15548627.2021.1985881. Epub 2021 Oct 13. Autophagy. 2021. PMID: 34643458 Free PMC article.
33 results