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Safety and humoral immunogenicity of the ChAdOx1 nCoV-19 vaccine administered as a fourth dose booster following two doses of ChAdOx1 nCoV-19 and a third dose of BNT162b2 (COV009): a prospective cohort study.
Feng S, Bibi S, Aley PK, Cappuccini F, Clutterbuck EA, Conlin K, Ebrahimi N, Eordogh A, Faust SN, Felle S, Green J, Gill H, Mujadidi Y, Oladunjoye I, Owino N, Plested E, Robinson H, Stuart A, Voysey M, Pollard AJ, Lambe T. Feng S, et al. Among authors: lambe t. J Infect. 2025 Jan 16:106423. doi: 10.1016/j.jinf.2025.106423. Online ahead of print. J Infect. 2025. PMID: 39826861 Free article.
Ebola disease: bridging scientific discoveries and clinical application.
Rojek A, Fieggen J, Apiyo P, Caluwaerts S, Fowler RA, Kaleebu P, Kojan R, Lado M, Lambe T, Dunning J, Horby P. Rojek A, et al. Among authors: lambe t. Lancet Infect Dis. 2024 Dec 12:S1473-3099(24)00673-X. doi: 10.1016/S1473-3099(24)00673-X. Online ahead of print. Lancet Infect Dis. 2024. PMID: 39675368 Review.
Systemic prime mucosal boost significantly increases protective efficacy of bivalent RSV influenza viral vectored vaccine.
Bissett C, Belij-Rammerstorfer S, Ulaszewska M, Smith H, Kailath R, Morris S, Powers C, Sebastian S, Sharpe HR, Allen ER, Wang Z, Cunliffe RF, Sallah HJ, Spencer AJ, Gilbert S, Tregoning JS, Lambe T. Bissett C, et al. Among authors: lambe t. NPJ Vaccines. 2024 Jun 26;9(1):118. doi: 10.1038/s41541-024-00912-1. NPJ Vaccines. 2024. PMID: 38926455 Free PMC article.
Potent immunogenicity and protective efficacy of a multi-pathogen vaccination targeting Ebola, Sudan, Marburg and Lassa viruse.
Flaxman A, Sebastian S, Appelberg S, Cha KM, Ulaszewska M, Purushotham J, Gilbride C, Sharpe H, Spencer AJ, Bibi S, Wright D, Schmidt I, Dowall S, Easterbrook L, Findlay-Wilson S, Gilbert S, Mirazimi A, Lambe T. Flaxman A, et al. Among authors: lambe t. PLoS Pathog. 2024 Jun 26;20(6):e1012262. doi: 10.1371/journal.ppat.1012262. eCollection 2024 Jun. PLoS Pathog. 2024. PMID: 38924060 Free PMC article.
Immunogenicity and safety of beta variant COVID-19 vaccine AZD2816 and AZD1222 (ChAdOx1 nCoV-19) as primary-series vaccination for previously unvaccinated adults in Brazil, South Africa, Poland, and the UK: a randomised, partly double-blinded, phase 2/3 non-inferiority immunobridging study.
Costa Clemens SA, Jepson B, Bhorat QE, Ahmad A, Akhund T, Aley PK, Bansal H, Bibi S, Kelly EJ, Khan M, Lambe T, Lombaard JJ, Matthews S, Pipolo Milan E, Olsson U, Ramasamy MN, Moura de Oliveira Paiva MS, Seegobin S, Shoemaker K, Szylak A, Villafana T, Pollard AJ, Green JA; AZD2816 Study Group. Costa Clemens SA, et al. Among authors: lambe t. Lancet Microbe. 2024 Aug;5(8):100863. doi: 10.1016/S2666-5247(24)00078-8. Epub 2024 Jun 12. Lancet Microbe. 2024. PMID: 38878794 Free article. Clinical Trial.
Safety and immunogenicity of ChAdOx1 nCoV-19 (AZD1222) vaccine in adults in Kenya: a phase 1/2 single-blind, randomised controlled trial.
Hamaluba M, Sang S, Orindi B, Njau I, Karanja H, Kamau N, Gitonga JN, Mugo D, Wright D, Nyagwange J, Kutima B, Omuoyo D, Mwatasa M, Ngetsa C, Agoti C, Cheruiyot S, Nyaguara A, Munene M, Mturi N, Oloo E, Ochola-Oyier L, Mumba N, Mauncho C, Namayi R, Davies A, Tsofa B, Nduati EW, Aliyan N, Kasera K, Etyang A, Boyd A, Hill A, Gilbert S, Douglas A, Pollard A, Bejon P, Lambe T, Warimwe G; COV004 Vaccine Trial Group. Hamaluba M, et al. Among authors: lambe t. Wellcome Open Res. 2023 Nov 27;8:182. doi: 10.12688/wellcomeopenres.19150.2. eCollection 2023. Wellcome Open Res. 2023. PMID: 38707489 Free PMC article.
Multi-omics analysis reveals COVID-19 vaccine induced attenuation of inflammatory responses during breakthrough disease.
Drury RE, Camara S, Chelysheva I, Bibi S, Sanders K, Felle S, Emary K, Phillips D, Voysey M, Ferreira DM, Klenerman P, Gilbert SC, Lambe T, Pollard AJ, O'Connor D. Drury RE, et al. Among authors: lambe t. Nat Commun. 2024 Apr 22;15(1):3402. doi: 10.1038/s41467-024-47463-6. Nat Commun. 2024. PMID: 38649734 Free PMC article. Clinical Trial.
A Bivalent Adenovirus-Vectored Vaccine Induces a Robust Humoral Response, but Does Not Protect Cynomolgus Macaques Against a Lethal Challenge With Sudan Virus.
van Tol S, Fletcher P, Feldmann F, Mukesh RK, Port JR, Gallogly S, Schulz JE, Rhoderick JF, Makinson R, Carmody A, Myers L, Lovaglio J, Smith BJ, Okumura A, Shaia C, Saturday G, Marzi A, Lambe T, Munster VJ, van Doremalen N. van Tol S, et al. Among authors: lambe t. J Infect Dis. 2024 Nov 15;230(5):1083-1092. doi: 10.1093/infdis/jiae056. J Infect Dis. 2024. PMID: 38487996 Free PMC article.
204 results