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Biology-inspired dynamic microphysiological system approaches to revolutionize basic research, healthcare and animal welfare.
Marx U, Beken S, Chen Z, Dehne EM, Doherty A, Ewart L, Fitzpatrick SC, Griffith LG, Gu Z, Hartung T, Hickman J, Ingber DE, Ishida S, Jeong J, Leist M, Levin L, Mendrick DL, Pallocca G, Platz S, Raschke M, Smirnova L, Tagle DA, Trapecar M, van Balkom BWM, van den Eijnden-van Raaij J, van der Meer A, Roth A. Marx U, et al. Among authors: dehne em. ALTEX. 2025 Jan 17. doi: 10.14573/altex.2410112. Online ahead of print. ALTEX. 2025. PMID: 39827406
Recommendations on fit-for-purpose criteria to establish quality management for microphysiological systems and for monitoring their reproducibility.
Pamies D, Ekert J, Zurich MG, Frey O, Werner S, Piergiovanni M, Freedman BS, Keong Teo AK, Erfurth H, Reyes DR, Loskill P, Candarlioglu P, Suter-Dick L, Wang S, Hartung T, Coecke S, Stacey GN, Wagegg BA, Dehne EM, Pistollato F, Leist M. Pamies D, et al. Among authors: dehne em. Stem Cell Reports. 2024 Jul 2;19(7):1041. doi: 10.1016/j.stemcr.2024.06.007. Online ahead of print. Stem Cell Reports. 2024. PMID: 38959889 Free PMC article. No abstract available.
Recommendations on fit-for-purpose criteria to establish quality management for microphysiological systems and for monitoring their reproducibility.
Pamies D, Ekert J, Zurich MG, Frey O, Werner S, Piergiovanni M, Freedman BS, Keong Teo AK, Erfurth H, Reyes DR, Loskill P, Candarlioglu P, Suter-Dick L, Wang S, Hartung T, Coecke S, Stacey GN, Wagegg BA, Dehne EM, Pistollato F, Leist M. Pamies D, et al. Among authors: dehne em. Stem Cell Reports. 2024 May 14;19(5):604-617. doi: 10.1016/j.stemcr.2024.03.009. Epub 2024 Apr 25. Stem Cell Reports. 2024. PMID: 38670111 Free PMC article. Review.
Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development.
Marx U, Akabane T, Andersson TB, Baker E, Beilmann M, Beken S, Brendler-Schwaab S, Cirit M, David R, Dehne EM, Durieux I, Ewart L, Fitzpatrick SC, Frey O, Fuchs F, Griffith LG, Hamilton GA, Hartung T, Hoeng J, Hogberg H, Hughes DJ, Ingber DE, Iskandar A, Kanamori T, Kojima H, Kuehnl J, Leist M, Li B, Loskill P, Mendrick DL, Neumann T, Pallocca G, Rusyn I, Smirnova L, Steger-Hartmann T, Tagle DA, Tonevitsky A, Tsyb S, Trapecar M, Van de Water B, Van den Eijnden-van Raaij J, Vulto P, Watanabe K, Wolf A, Zhou X, Roth A. Marx U, et al. Among authors: dehne em. ALTEX. 2020;37(3):365-394. doi: 10.14573/altex.2001241. Epub 2020 Feb 28. ALTEX. 2020. PMID: 32113184 Free PMC article.
Autologous induced pluripotent stem cell-derived four-organ-chip.
Ramme AP, Koenig L, Hasenberg T, Schwenk C, Magauer C, Faust D, Lorenz AK, Krebs AC, Drewell C, Schirrmann K, Vladetic A, Lin GC, Pabinger S, Neuhaus W, Bois F, Lauster R, Marx U, Dehne EM. Ramme AP, et al. Among authors: dehne em. Future Sci OA. 2019 Sep 10;5(8):FSO413. doi: 10.2144/fsoa-2019-0065. Future Sci OA. 2019. PMID: 31534781 Free PMC article.
Application of Microphysiological Systems to Enhance Safety Assessment in Drug Discovery.
Ewart L, Dehne EM, Fabre K, Gibbs S, Hickman J, Hornberg E, Ingelman-Sundberg M, Jang KJ, Jones DR, Lauschke VM, Marx U, Mettetal JT, Pointon A, Williams D, Zimmermann WH, Newham P. Ewart L, et al. Among authors: dehne em. Annu Rev Pharmacol Toxicol. 2018 Jan 6;58:65-82. doi: 10.1146/annurev-pharmtox-010617-052722. Epub 2017 Oct 13. Annu Rev Pharmacol Toxicol. 2018. PMID: 29029591 Review.
13 results