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Structure-Based Discovery and Development of Highly Potent Dihydroorotate Dehydrogenase Inhibitors for Malaria Chemoprevention.
Nie Z, Bonnert R, Tsien J, Deng X, Higgs C, El Mazouni F, Zhang X, Li R, Ho N, Feher V, Paulsen J, Shackleford DM, Katneni K, Chen G, Ng ACF, McInerney M, Wang W, Saunders J, Collins D, Yan D, Li P, Campbell M, Patil R, Ghoshal A, Mondal P, Kundu A, Chittimalla R, Mahadeva M, Kokkonda S, White J, Das R, Mukherjee P, Angulo-Barturen I, Jiménez-Díaz MB, Malmstrom R, Lawrenz M, Rodriguez-Granillo A, Rathod PK, Tomchick DR, Palmer MJ, Laleu B, Qin T, Charman SA, Phillips MA. Nie Z, et al. Among authors: mcinerney m. J Med Chem. 2025 Jan 9;68(1):590-637. doi: 10.1021/acs.jmedchem.4c02394. Epub 2024 Dec 22. J Med Chem. 2025. PMID: 39710971 Free PMC article.
MR1 presents vitamin B6-related compounds for recognition by MR1-reactive T cells.
McInerney MP, Awad W, Souter MNT, Kang Y, Wang CJH, Chan Yew Poa K, Abdelaal MR, Le NH, Shepherd CM, McNeice C, Meehan LJ, Nelson AG, Raynes JM, Mak JYW, McCluskey J, Chen Z, Ang CS, Fairlie DP, Le Nours J, Illing PT, Rossjohn J, Purcell AW. McInerney MP, et al. Proc Natl Acad Sci U S A. 2024 Dec 3;121(49):e2414792121. doi: 10.1073/pnas.2414792121. Epub 2024 Nov 26. Proc Natl Acad Sci U S A. 2024. PMID: 39589872
Cohort profile: the CARTaGENE Cohort Nutrition Study (Quebec, Canada).
Ho V, Csizmadi I, Boucher BA, McInerney M, Boileau C, Noisel N, Payette Y, Awadalla P, Koushik A. Ho V, et al. Among authors: mcinerney m. BMJ Open. 2024 Aug 17;14(8):e083425. doi: 10.1136/bmjopen-2023-083425. BMJ Open. 2024. PMID: 39153764 Free PMC article.
Metaproteomics-informed stoichiometric modeling reveals the responses of wetland microbial communities to oxygen and sulfate exposure.
Wang D, Candry P, Hunt KA, Flinkstrom Z, Shi Z, Liu Y, Wofford NQ, McInerney MJ, Tanner RS, De Leόn KB, Zhou J, Winkler MH, Stahl DA, Pan C. Wang D, et al. Among authors: mcinerney mj. NPJ Biofilms Microbiomes. 2024 Jul 3;10(1):55. doi: 10.1038/s41522-024-00525-5. NPJ Biofilms Microbiomes. 2024. PMID: 38961111 Free PMC article.
216 results