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A new hypothesis to explain disease dominance.
Juvik B, Falcucci L, Lundegaard PR, Stainier DYR. Juvik B, et al. Among authors: stainier dyr. Trends Genet. 2025 Jan 2:S0168-9525(24)00291-9. doi: 10.1016/j.tig.2024.11.009. Online ahead of print. Trends Genet. 2025. PMID: 39788833 Free article. Review.
PDGFRA is a conserved HAND2 effector during early cardiac development.
Xu Y, Gehlot R, Capon SJ, Albu M, Gretz J, Bloomekatz J, Mattonet K, Vucicevic D, Talyan S, Kikhi K, Günther S, Looso M, Firulli BA, Sanda M, Firulli AB, Lacadie SA, Yelon D, Stainier DYR. Xu Y, et al. Among authors: stainier dyr. Nat Cardiovasc Res. 2024 Dec;3(12):1531-1548. doi: 10.1038/s44161-024-00574-1. Epub 2024 Dec 10. Nat Cardiovasc Res. 2024. PMID: 39658721 Free PMC article.
Pathogenic proteotoxicity of cryptic splicing is alleviated by ubiquitination and ER-phagy.
Prieto-Garcia C, Matkovic V, Mosler T, Li C, Liang J, Oo JA, Haidle F, Mačinković I, Cabrera-Orefice A, Berkane R, Giuliani G, Xu F, Jacomin AC, Tomaskovic I, Basoglu M, Hoffmann ME, Rathore R, Cetin R, Boutguetait D, Bozkurt S, Hernández Cañás MC, Keller M, Busam J, Shah VJ, Wittig I, Kaulich M, Beli P, Galej WP, Ebersberger I, Wang L, Münch C, Stolz A, Brandes RP, Tse WKF, Eimer S, Stainier DYR, Legewie S, Zarnack K, Müller-McNicoll M, Dikic I. Prieto-Garcia C, et al. Among authors: stainier dyr. Science. 2024 Nov 15;386(6723):768-776. doi: 10.1126/science.adi5295. Epub 2024 Nov 14. Science. 2024. PMID: 39541449
The heart is a resident tissue for hematopoietic stem and progenitor cells in zebrafish.
Bornhorst D, Hejjaji AV, Steuter L, Woodhead NM, Maier P, Gentile A, Alhajkadour A, Santis Larrain O, Weber M, Kikhi K, Guenther S, Huisken J, Tamplin OJ, Stainier DYR, Gunawan F. Bornhorst D, et al. Among authors: stainier dyr. Nat Commun. 2024 Aug 31;15(1):7589. doi: 10.1038/s41467-024-51920-7. Nat Commun. 2024. PMID: 39217144 Free PMC article.
273 results