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First-in-Human clinical trial of a small molecule EBNA1 inhibitor, VK-2019, in patients with Epstein-Barr positive nasopharyngeal cancer, with pharmacokinetic and pharmacodynamic studies.
Colevas AD, Talebi Z, Winters E, Even C, Lee VH, Gillison ML, Khan SA, Lu R, Pinsky BA, Soldan SS, Vladmirova O, Lieberman PM, Messick TE. Colevas AD, et al. Among authors: vladmirova o. Clin Cancer Res. 2025 Jan 20. doi: 10.1158/1078-0432.CCR-24-2814. Online ahead of print. Clin Cancer Res. 2025. PMID: 39831818