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Aging-induced changes in lymphatic muscle cell transcriptomes are associated with reduced pumping of peripheral collecting lymphatic vessels in mice.
Lei PJ, Ruscic KJ, Roh K, Rajotte JJ, O'Melia MJ, Bouta EM, Marquez M, Pereira ER, Kumar AS, Razavi MS, Zhou H, Menzel L, Huang L, Kumra H, Duquette M, Huang P, Baish JW, Munn LL, Kurpios NA, Ubellacker JM, Padera TP. Lei PJ, et al. Dev Cell. 2024 Dec 19:S1534-5807(24)00732-9. doi: 10.1016/j.devcel.2024.12.010. Online ahead of print. Dev Cell. 2024. PMID: 39731913
Reprogramming the Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-PD-1 Therapy.
Chen J, Amoozgar Z, Liu X, Aoki S, Liu Z, Shin SM, Matsui A, Hernandez A, Pu Z, Halvorsen S, Lei PJ, Datta M, Zhu L, Ruan Z, Shi L, Staiculescu D, Inoue K, Munn LL, Fukumura D, Huang P, Sassi S, Bardeesy N, Ho WJ, Jain RK, Duda DG. Chen J, et al. Among authors: lei pj. Cancer Immunol Res. 2024 Apr 2;12(4):400-412. doi: 10.1158/2326-6066.CIR-23-0486. Cancer Immunol Res. 2024. PMID: 38260999 Free PMC article.
Lymphatic muscle cells are unique cells that undergo aging induced changes.
Lei PJ, Ruscic KJ, Roh K, Rajotte JJ, O'Melia MJ, Bouta EM, Marquez M, Pereira ER, Kumar AS, Arroyo-Ataz G, Razavi MS, Zhou H, Menzel L, Kumra H, Duquette M, Huang P, Baish JW, Munn LL, Ubellacker JM, Jones D, Padera TP. Lei PJ, et al. bioRxiv [Preprint]. 2023 Nov 19:2023.11.18.567621. doi: 10.1101/2023.11.18.567621. bioRxiv. 2023. Update in: Dev Cell. 2024 Dec 19:S1534-5807(24)00732-9. doi: 10.1016/j.devcel.2024.12.010 PMID: 38014141 Free PMC article. Updated. Preprint.
Cancer immunotherapy response persists after lymph node resection.
Zhou H, Menzel L, Baish JW, O'Melia MJ, Darragh LB, Specht E, Effiom DN, Czapla J, Lei PJ, Rajotte JJ, Liu L, Nikmaneshi MR, Razavi MS, Vander Heiden MG, Ubellacker JM, Munn LL, Karam SD, Boland GM, Cohen S, Padera TP. Zhou H, et al. Among authors: lei pj. bioRxiv [Preprint]. 2024 Dec 11:2023.09.19.558262. doi: 10.1101/2023.09.19.558262. bioRxiv. 2024. PMID: 37781599 Free PMC article. Preprint.
28 results