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Mitochondrial respiratory complex III sustains IL-10 production in activated macrophages and promotes tumor-mediated immune evasion.
Zotta A, Toller-Kawahisa J, Palsson-McDermott EM, O'Carroll SM, Henry ÓC, Day EA, McGettrick AF, Ward RW, Ryan DG, Watson MA, Brand MD, Runtsch MC, Maitz K, Lueger A, Kargl J, Miljkovic JL, Lavelle EC, O'Neill LAJ. Zotta A, et al. Sci Adv. 2025 Jan 24;11(4):eadq7307. doi: 10.1126/sciadv.adq7307. Epub 2025 Jan 22. Sci Adv. 2025. PMID: 39841829 Free article.
Metabolic reprogramming of macrophages by PKM2 promotes IL-10 production via adenosine.
Toller-Kawahisa JE, Viacava PR, Palsson-McDermott EM, Nascimento DC, Cervantes-Silva MP, O'Carroll SM, Zotta A, Damasceno LEA, Públio GA, Forti P, Luiz JPM, Silva de Melo BM, Martins TV, Faça VM, Curtis A, Cunha TM, Cunha FQ, O'Neill LAJ, Alves-Filho JC. Toller-Kawahisa JE, et al. Among authors: zotta a. Cell Rep. 2025 Jan 7;44(1):115172. doi: 10.1016/j.celrep.2024.115172. Online ahead of print. Cell Rep. 2025. PMID: 39772395 Free article.
Author Correction: Itaconate drives mtRNA-mediated type I interferon production through inhibition of succinate dehydrogenase.
O'Carroll SM, Peace CG, Toller-Kawahisa JE, Min Y, Hooftman A, Charki S, Kehoe L, O'Sullivan MJ, Zoller A, Mcgettrick AF, Zotta A, Day EA, Simarro M, Armstrong N, Annes JP, O'Neill LAJ. O'Carroll SM, et al. Among authors: zotta a. Nat Metab. 2024 Dec 12. doi: 10.1038/s42255-024-01204-7. Online ahead of print. Nat Metab. 2024. PMID: 39668260 No abstract available.
Neoadjuvant Immunotherapy in Head and Neck Cancers: A Paradigm Shift in Treatment Approach.
Zotta A, Marciano ML, Sabbatino F, Ottaiano A, Cascella M, Pontone M, Montano M, Calogero E, Longo F, Fasano M, Troiani T, Ciardiello F, Rampetta FR, Salzano G, Dell'Aversana Orabona G, Califano L, Ionna F, Perri F. Zotta A, et al. Biomedicines. 2024 Oct 14;12(10):2337. doi: 10.3390/biomedicines12102337. Biomedicines. 2024. PMID: 39457649 Free PMC article. Review.
Itaconate drives mtRNA-mediated type I interferon production through inhibition of succinate dehydrogenase.
O'Carroll SM, Peace CG, Toller-Kawahisa JE, Min Y, Hooftman A, Charki S, Kehoe L, O'Sullivan MJ, Zoller A, Mcgettrick AF, Zotta A, Day EA, Simarro M, Armstrong N, Annes JP, O'Neill LAJ. O'Carroll SM, et al. Among authors: zotta a. Nat Metab. 2024 Nov;6(11):2060-2069. doi: 10.1038/s42255-024-01145-1. Epub 2024 Oct 15. Nat Metab. 2024. PMID: 39406969
Temozolomide based treatment in glioblastoma: 6 vs. 12 months.
Fasano M, Pirozzi M, De Falco V, Miceli CC, Farese S, Zotta A, Famiglietti V, Vitale P, Di Giovanni I, Brancati C, Carfora V, Solari D, Somma T, Cavallo LM, Cappabianca P, Conson M, Pacelli R, Ciardiello F, Addeo R. Fasano M, et al. Among authors: zotta a. Oncol Lett. 2024 Jul 2;28(3):418. doi: 10.3892/ol.2024.14551. eCollection 2024 Sep. Oncol Lett. 2024. PMID: 39006948 Free PMC article.
Translational Insights in the Landscape of Salivary Gland Cancers: Ready for a New Era?
Perri F, Fusco R, Sabbatino F, Fasano M, Ottaiano A, Cascella M, Marciano ML, Pontone M, Salzano G, Maiello ME, Montano M, Calogero E, D'Aniello R, Maiolino P, Ciardiello F, Zotta A, Alfieri S, Ionna F. Perri F, et al. Among authors: zotta a. Cancers (Basel). 2024 Feb 28;16(5):970. doi: 10.3390/cancers16050970. Cancers (Basel). 2024. PMID: 38473330 Free PMC article. Review.
Modified blade: an interventional option in rigid bronchoscopy for non-resectable benign tracheal stenosis.
Messina G, Di Filippo V, Capasso F, Puca MA, Leonardi B, Grande M, Rainone A, Leone F, Vicario G, De Gregorio S, Cerullo G, Ponticiello A, Pirozzi M, Farese S, Zotta A, Natale G, Messina G, Vicidomini G, Fiorelli A, Ciardiello F, Fasano M. Messina G, et al. Among authors: zotta a. J Cardiothorac Surg. 2024 Feb 8;19(1):73. doi: 10.1186/s13019-024-02576-3. J Cardiothorac Surg. 2024. PMID: 38331792 Free PMC article.
27 results