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Page 1
Polygenic risk discriminates Lewy body dementia from Alzheimer's disease.
McKeever A, Swann P, Malpetti M, Donaghy PC, Thomas A, Mak E, Carter SF, Tan JHK, Hong YT, Fryer TD, Heslegrave A, Zetterberg H, Su L, Chouliaras L, Rowe JB, O'Brien JT. McKeever A, et al. Among authors: heslegrave a. Alzheimers Dement. 2025 Jan 24:e14381. doi: 10.1002/alz.14381. Online ahead of print. Alzheimers Dement. 2025. PMID: 39853853
Somatic CAG repeat expansion in blood associates with biomarkers of neurodegeneration in Huntington's disease decades before clinical motor diagnosis.
Scahill RI, Farag M, Murphy MJ, Hobbs NZ, Leocadi M, Langley C, Knights H, Ciosi M, Fayer K, Nakajima M, Thackeray O, Gobom J, Rönnholm J, Weiner S, Hassan YR, Ponraj NKP, Estevez-Fraga C, Parker CS, Malone IB, Hyare H, Long JD, Heslegrave A, Sampaio C, Zhang H, Robbins TW, Zetterberg H, Wild EJ, Rees G, Rowe JB, Sahakian BJ, Monckton DG, Langbehn DR, Tabrizi SJ. Scahill RI, et al. Among authors: heslegrave a. Nat Med. 2025 Jan 17. doi: 10.1038/s41591-024-03424-6. Online ahead of print. Nat Med. 2025. PMID: 39825149
How well do plasma Alzheimer's disease biomarkers reflect the CSF amyloid status?
Hazan J, Abel E, Rosa Grilo M, Alawode D, Laranjinha I, Heslegrave AJ, Liu KY, Schott JM, Howard R, Zetterberg H, Fox NC. Hazan J, et al. Among authors: heslegrave aj. J Neurol Neurosurg Psychiatry. 2024 Dec 18:jnnp-2024-334122. doi: 10.1136/jnnp-2024-334122. Online ahead of print. J Neurol Neurosurg Psychiatry. 2024. PMID: 39694821 Free article.
More than microglia: myeloid cells and biomarkers in neurodegeneration.
Kodosaki E, Bell R, Sogorb-Esteve A, Wiltshire K, Zetterberg H, Heslegrave A. Kodosaki E, et al. Among authors: heslegrave a. Front Neurosci. 2024 Oct 31;18:1499458. doi: 10.3389/fnins.2024.1499458. eCollection 2024. Front Neurosci. 2024. PMID: 39544911 Free PMC article. Review.
Neurodegenerative fluid biomarkers are enriched in human cervical lymph nodes.
Al-Diwani A, Provine NM, Murchison A, Laban R, Swann OJ, Koychev I, Sheerin F, Da Mesquita S, Heslegrave A, Zetterberg H, Klenerman P, Irani SR. Al-Diwani A, et al. Among authors: heslegrave a. Brain. 2024 Oct 21:awae329. doi: 10.1093/brain/awae329. Online ahead of print. Brain. 2024. PMID: 39432679
Poor long-term outcomes and abnormal neurodegeneration biomarkers after military traumatic brain injury: the ADVANCE study.
Graham NS, Blissitt G, Zimmerman K, Orton L, Friedland D, Coady E, Laban R, Veleva E, Heslegrave AJ, Zetterberg H, Schofield S, Fear NT, Boos CJ, Bull AMJ, Bennett A, Sharp DJ; ADVANCE Study. Graham NS, et al. Among authors: heslegrave aj. J Neurol Neurosurg Psychiatry. 2025 Jan 16;96(2):105-113. doi: 10.1136/jnnp-2024-333777. J Neurol Neurosurg Psychiatry. 2025. PMID: 39393903 Free article.
Persistent delirium is associated with cerebrospinal fluid markers of neuronal injury.
Tsui A, Johnstone B, Heslegrave A, Zetterberg H, Watne LO, Neerland BE, Krogseth M, Cunningham C, MacLullich A, Muniz Terrera G, Davis D, Caplan G. Tsui A, et al. Among authors: heslegrave a. Brain Commun. 2024 Sep 18;6(5):fcae319. doi: 10.1093/braincomms/fcae319. eCollection 2024. Brain Commun. 2024. PMID: 39355007 Free PMC article.
P-tau217 and other blood biomarkers of dementia: variation with time of day.
Della Monica C, Revell V, Atzori G, Laban R, Skene SS, Heslegrave A, Hassanin H, Nilforooshan R, Zetterberg H, Dijk DJ. Della Monica C, et al. Among authors: heslegrave a. Transl Psychiatry. 2024 Sep 13;14(1):373. doi: 10.1038/s41398-024-03084-7. Transl Psychiatry. 2024. PMID: 39271655 Free PMC article.
161 results