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Postdiscontinuation Antibiotic Exposure in Hospitalized Infants at Risk for Late-onset Sepsis in the Neonatal Intensive Care Unit.
Wade KC, Greenberg RG, Benjamin DK Jr, Chen LL, Vo B, Ang BL, Boutzoukas A, Zimmerman K, Clark RH, Cohen-Wolkowiez M, Le J; Administrative Core Committee of the Best Pharmaceuticals for Children Act – Pediatric Trials Network. Wade KC, et al. Pediatr Infect Dis J. 2024 Oct 1;43(10):991-996. doi: 10.1097/INF.0000000000004426. Epub 2024 Jun 17. Pediatr Infect Dis J. 2024. PMID: 38900075
Physiologically-based pharmacokinetic modeling of pantoprazole to evaluate the role of CYP2C19 genetic variation and obesity in the pediatric population.
Thompson EJ, Jeong A, Helfer VE, Shakhnovich V, Edginton A, Balevic SJ, James LP, Collier DN, Anand R, Gonzalez D; Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee. Thompson EJ, et al. CPT Pharmacometrics Syst Pharmacol. 2024 Aug;13(8):1394-1408. doi: 10.1002/psp4.13167. Epub 2024 Jun 4. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 38837864 Free PMC article. Clinical Trial.
Application of Physiologically Based Pharmacokinetic Modeling to Characterize the Effects of Age and Obesity on the Disposition of Levetiracetam in the Pediatric Population.
Maglalang PD, Sinha J, Zimmerman K, McCann S, Edginton A, Hornik CP, Hornik CD, Muller WJ, Al-Uzri A, Meyer M, Chen JY, Anand R, Perrin EM, Gonzalez D; Best Pharmaceuticals for Children Act–Pediatric Trials Network Steering Committee. Maglalang PD, et al. Clin Pharmacokinet. 2024 Jun;63(6):885-899. doi: 10.1007/s40262-024-01367-2. Epub 2024 May 30. Clin Pharmacokinet. 2024. PMID: 38814425
Opportunistic dried blood spot sampling validates and optimizes a pediatric population pharmacokinetic model of metronidazole.
Randell RL, Balevic SJ, Greenberg RG, Cohen-Wolkowiez M, Thompson EJ, Venkatachalam S, Smith MJ, Bendel C, Bliss JM, Chaaban H, Chhabra R, Dammann CEL, Downey LC, Hornik C, Hussain N, Laughon MM, Lavery A, Moya F, Saxonhouse M, Sokol GM, Trembath A, Weitkamp J-H, Hornik CP; Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee. Randell RL, et al. Antimicrob Agents Chemother. 2024 Apr 3;68(4):e0153323. doi: 10.1128/aac.01533-23. Epub 2024 Mar 14. Antimicrob Agents Chemother. 2024. PMID: 38477706 Free PMC article.
Use of physiologically-based pharmacokinetic modeling to inform dosing of the opioid analgesics fentanyl and methadone in children with obesity.
Gerhart JG, Carreño FO, Ford JL, Edginton AN, Perrin EM, Watt KM, Muller WJ, Atz AM, Al-Uzri A, Delmore P, Gonzalez D; Best Pharmaceuticals for Children Act-Pediatric Trials Network Steering Committee. Gerhart JG, et al. Among authors: delmore p. CPT Pharmacometrics Syst Pharmacol. 2022 Jun;11(6):778-791. doi: 10.1002/psp4.12793. Epub 2022 May 2. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35491971 Free PMC article.
Use of Real-World Data and Physiologically-Based Pharmacokinetic Modeling to Characterize Enoxaparin Disposition in Children With Obesity.
Gerhart JG, Carreño FO, Loop MS, Lee CR, Edginton AN, Sinha J, Kumar KR, Kirkpatrick CM, Hornik CP, Gonzalez D; Best Pharmaceuticals for Children Act - Pediatric Trials Network Steering Committee. Gerhart JG, et al. Clin Pharmacol Ther. 2022 Aug;112(2):391-403. doi: 10.1002/cpt.2618. Epub 2022 May 18. Clin Pharmacol Ther. 2022. PMID: 35451072 Free PMC article.
Development and Evaluation of a Virtual Population of Children with Obesity for Physiologically Based Pharmacokinetic Modeling.
Gerhart JG, Carreño FO, Edginton AN, Sinha J, Perrin EM, Kumar KR, Rikhi A, Hornik CP, Harris V, Ganguly S, Cohen-Wolkowiez M, Gonzalez D; Best Pharmaceuticals for Children Act—Pediatric Trials Network Steering Committee. Gerhart JG, et al. Clin Pharmacokinet. 2022 Feb;61(2):307-320. doi: 10.1007/s40262-021-01072-4. Epub 2021 Oct 7. Clin Pharmacokinet. 2022. PMID: 34617262 Free PMC article.
Pharmacokinetics of Ceftazidime in Children and Adolescents with Obesity.
Maharaj AR, Wu H, Zimmerman KO, Muller WJ, Sullivan JE, Sherwin CMT, Autmizguine J, Rathore MH, Hornik CD, Al-Uzri A, Payne EH, Benjamin DK Jr, Hornik CP; Best Pharmaceuticals for Children Act-Pediatric Trials Network Steering Committee. Maharaj AR, et al. Paediatr Drugs. 2021 Sep;23(5):499-513. doi: 10.1007/s40272-021-00460-4. Epub 2021 Jul 23. Paediatr Drugs. 2021. PMID: 34302290 Free PMC article.
Physiologically Based Pharmacokinetic Modeling of Meropenem in Preterm and Term Infants.
Ganguly S, Edginton AN, Gerhart JG, Cohen-Wolkowiez M, Greenberg RG, Gonzalez D; Best Pharmaceuticals for Children Act-Pediatric Trials Network Steering Committee. Ganguly S, et al. Clin Pharmacokinet. 2021 Dec;60(12):1591-1604. doi: 10.1007/s40262-021-01046-6. Epub 2021 Jun 22. Clin Pharmacokinet. 2021. PMID: 34155614 Free PMC article.
58 results