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Page 1
Ketomethylureas. A new class of angiotensin converting enzyme inhibitors.
Natarajan S, Gordon EM, Sabo EF, Godfrey JD, Weller HN, Pluscec J, Rom MB, Engebrecht J, Cushman DW, Deforrest JM, et al. Natarajan S, et al. Among authors: godfrey jd. J Enzyme Inhib. 1988;2(2):91-7. doi: 10.3109/14756368809040715. J Enzyme Inhib. 1988. PMID: 3236070
Arylpropanolamines: selective beta3 agonists arising from strategies to mitigate phase I metabolic transformations.
Washburn WN, Harper TW, Wu G, Godfrey JD, McCann P, Girotra R, Shao C, Zhang H, Gavai A, Mikkilineni A, Dejneka T, Ahmed S, Caringal Y, Hangeland J, Zhang M, Cheng PT, Russell AD, Skwish S, Slusarchyk DA, Allen GT, Frohlich BH, Abboa-Offei BE, Cap M, Waldron TL, George RJ, Tesfamariam B, Dickinson KE, Seymour AA, Sher PM. Washburn WN, et al. Among authors: godfrey jd. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4290-6. doi: 10.1016/j.bmcl.2007.05.030. Epub 2007 May 16. Bioorg Med Chem Lett. 2007. PMID: 17533126
Addition of benzylic and allylic organozinc and Grignard reagents to resin-bound imines to provide alpha-branched secondary amines bearing a wide variety of functional groups. Utility in the synthesis of beta-3 adrenergic receptor agonists.
Wu G, Cai ZW, Bednarz MS, Kocy OR, Gavai AV, Godfrey JD Jr, Washburn WN, Poss MA, Sher PM. Wu G, et al. Among authors: godfrey jd jr. J Comb Chem. 2005 Jan-Feb;7(1):99-108. doi: 10.1021/cc0498682. J Comb Chem. 2005. PMID: 15638488
Novel 1,4-homofragmentation via an alpha-lactone.
Godfrey JD Jr, Fox RT, Buono FG, Gougoutas JZ, Malley MF. Godfrey JD Jr, et al. J Org Chem. 2006 Oct 27;71(22):8647-50. doi: 10.1021/jo0613380. J Org Chem. 2006. PMID: 17064050
Efficient asymmetric synthesis of the vasopeptidase inhibitor BMS-189921.
Singh J, Kronenthal DR, Schwinden M, Godfrey JD, Fox R, Vawter EJ, Zhang B, Kissick TP, Patel B, Mneimne O, Humora M, Papaioannou CG, Szymanski W, Wong MK, Chen CK, Heikes JE, DiMarco JD, Qiu J, Deshpande RP, Gougoutas JZ, Mueller RH. Singh J, et al. Among authors: godfrey jd. Org Lett. 2003 Aug 21;5(17):3155-8. doi: 10.1021/ol0352308. Org Lett. 2003. PMID: 12917005
32 results