Durant GJ - Search Results

1

Pharmacological characterization of GT-2016, a non-thiourea-containing histamine H3 receptor antagonist: in vitro and in vivo studies.

Tedford CE, Yates SL, Pawlowski GP, Nalwalk JW, Hough LB, Khan MA, Phillips JG, Durant GJ, Frederickson RC. Tedford CE, et al. Among authors: durant gj. J Pharmacol Exp Ther. 1995 Nov;275(2):598-604. J Pharmacol Exp Ther. 1995. PMID: 7473144

2

H3 receptor antagonist, thioperamide, inhibits adrenal steroidogenesis and histamine binding to adrenocortical microsomes and binds to cytochrome P450.

LaBella FS, Queen G, Glavin G, Durant G, Stein D, Brandes LJ. LaBella FS, et al. Br J Pharmacol. 1992 Sep;107(1):161-4. doi: 10.1111/j.1476-5381.1992.tb14480.x. Br J Pharmacol. 1992. PMID: 1330158 Free PMC article.

3

Toxicity of H2-receptor antagonists to isolated rat hepatocytes: structure-activity relationships.

Rush GF, Alberts D, Lupo S, Yodis LA, Brown TH, Durant GJ. Rush GF, et al. Among authors: durant gj. J Pharmacol Exp Ther. 1988 Jan;244(1):113-7. J Pharmacol Exp Ther. 1988. PMID: 2891842

4

Design, synthesis, and neurochemical evaluation of 2-amino-5-(alkoxycarbonyl)-3,4,5,6-tetrahydropyridines and 2-amino-5-(alkoxycarbonyl)-1,4,5,6-tetrahydropyrimidines as M1 muscarinic receptor agonists.

Dunbar PG, Durant GJ, Rho T, Ojo B, Huzl JJ 3rd, Smith DA, el-Assadi AA, Sbeih S, Ngur DO, Periyasamy S, et al. Dunbar PG, et al. Among authors: durant gj. J Med Chem. 1994 Aug 19;37(17):2774-82. doi: 10.1021/jm00043a016. J Med Chem. 1994. PMID: 8064804

5

Design, synthesis, and neurochemical evaluation of 5-(3-alkyl-1,2,4- oxadiazol-5-yl)-1,4,5,6-tetrahydropyrimidines as M1 muscarinic receptor agonists.

Dunbar PG, Durant GJ, Fang Z, Abuh YF, el-Assadi AA, Ngur DO, Periyasamy S, Hoss WP, Messer WS Jr. Dunbar PG, et al. Among authors: durant gj. J Med Chem. 1993 Apr 2;36(7):842-7. doi: 10.1021/jm00059a008. J Med Chem. 1993. PMID: 8464038

6

Cyanoguanidine-thiourea equivalence in the development of the histamine H2-receptor antagonist, cimetidine.

Durant GJ, Emmett JC, Ganellin CR, Miles PD, Parsons ME, Prain HD, White GR. Durant GJ, et al. J Med Chem. 1977 Jul;20(7):901-6. doi: 10.1021/jm00217a007. J Med Chem. 1977. PMID: 17751

7

Icotidine, an antagonist of histamine at both H1 and H2 receptors.

Ganellin CR, Blakemore RC, Brown TH, Cooper DG, Durant GJ, Harvey CA, Ife RJ, Owen DA, Parsons ME, Rasmussen AC, et al. Ganellin CR, et al. Among authors: durant gj. N Engl Reg Allergy Proc. 1986 Mar-Apr;7(2):126-33. doi: 10.2500/108854186779047762. N Engl Reg Allergy Proc. 1986. PMID: 2886901

8

Characterization and development of cimetidine as a histamine H2-receptor antagonist.

Brimblecombe RW, Duncan WA, Durant GJ, Emmett JC, Ganellin CR, Leslie GB, Parsons ME. Brimblecombe RW, et al. Among authors: durant gj. Gastroenterology. 1978 Feb;74(2 Pt 2):339-47. Gastroenterology. 1978. PMID: 23336

9

The histamine H2 receptor agonist impromidine: synthesis and structure-activity considerations.

Durant GJ, Ganellin CR, Hills DW, Miles PD, Parsons ME, Pepper ES, White GR. Durant GJ, et al. J Med Chem. 1985 Oct;28(10):1414-22. doi: 10.1021/jm00148a007. J Med Chem. 1985. PMID: 2931524

10

The pharmacology of cimetidine, a new histamine H2-receptor antagonist. 1975.

Brimblecombe RW, Duncan WA, Durant GJ, Ganellin CR, Parsons ME, Black JW. Brimblecombe RW, et al. Among authors: durant gj. Br J Pharmacol. 2010 Jul;160 Suppl 1(Suppl 1):S52-3. doi: 10.1111/j.1476-5381.2010.00854.x. Br J Pharmacol. 2010. PMID: 20590655 Free PMC article. No abstract available.

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