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Substitutions of aspartic acid for glycine-220 and of arginine for glycine-664 in the triple helix of the pro alpha 1(I) chain of type I procollagen produce lethal osteogenesis imperfecta and disrupt the ability of collagen fibrils to incorporate crystalline hydroxyapatite.
Culbert AA, Lowe MP, Atkinson M, Byers PH, Wallis GA, Kadler KE. Culbert AA, et al. Among authors: lowe mp. Biochem J. 1995 Nov 1;311 ( Pt 3)(Pt 3):815-20. doi: 10.1042/bj3110815. Biochem J. 1995. PMID: 7487936 Free PMC article.
Membrane transport: tethers and TRAPPs.
Lowe M. Lowe M. Curr Biol. 2000 Jun 1;10(11):R407-9. doi: 10.1016/s0960-9822(00)00505-4. Curr Biol. 2000. PMID: 10837242 Free article. Review.
124 results