Wynn TA - Search Results

1

Cytokine regulation of granuloma formation in schistosomiasis.

Wynn TA, Cheever AW. Wynn TA, et al. Curr Opin Immunol. 1995 Aug;7(4):505-11. doi: 10.1016/0952-7915(95)80095-6. Curr Opin Immunol. 1995. PMID: 7495514 Review.

2

Endothelial cells are activated by cytokine treatment to kill an intravascular parasite, Schistosoma mansoni, through the production of nitric oxide.

Oswald IP, Eltoum I, Wynn TA, Schwartz B, Caspar P, Paulin D, Sher A, James SL. Oswald IP, et al. Among authors: wynn ta. Proc Natl Acad Sci U S A. 1994 Feb 1;91(3):999-1003. doi: 10.1073/pnas.91.3.999. Proc Natl Acad Sci U S A. 1994. PMID: 7508126 Free PMC article.

3

Elevated expression of Th1 cytokines and nitric oxide synthase in the lungs of vaccinated mice after challenge infection with Schistosoma mansoni.

Wynn TA, Oswald IP, Eltoum IA, Caspar P, Lowenstein CJ, Lewis FA, James SL, Sher A. Wynn TA, et al. J Immunol. 1994 Dec 1;153(11):5200-9. J Immunol. 1994. PMID: 7525727

4

An IL-12-based vaccination method for preventing fibrosis induced by schistosome infection.

Wynn TA, Cheever AW, Jankovic D, Poindexter RW, Caspar P, Lewis FA, Sher A. Wynn TA, et al. Nature. 1995 Aug 17;376(6541):594-6. doi: 10.1038/376594a0. Nature. 1995. PMID: 7637808

5

Acute cerebral toxoplasmosis is induced by in vivo neutralization of TNF-alpha and correlates with the down-regulated expression of inducible nitric oxide synthase and other markers of macrophage activation.

Gazzinelli RT, Eltoum I, Wynn TA, Sher A. Gazzinelli RT, et al. Among authors: wynn ta. J Immunol. 1993 Oct 1;151(7):3672-81. J Immunol. 1993. PMID: 7690809

6

IL-12 exacerbates rather than suppresses T helper 2-dependent pathology in the absence of endogenous IFN-gamma.

Wynn TA, Jankovic D, Hieny S, Zioncheck K, Jardieu P, Cheever AW, Sher A. Wynn TA, et al. J Immunol. 1995 Apr 15;154(8):3999-4009. J Immunol. 1995. PMID: 7706739

7

IL-12 enhances vaccine-induced immunity to Schistosoma mansoni in mice and decreases T helper 2 cytokine expression, IgE production, and tissue eosinophilia.

Wynn TA, Jankovic D, Hieny S, Cheever AW, Sher A. Wynn TA, et al. J Immunol. 1995 May 1;154(9):4701-9. J Immunol. 1995. PMID: 7722323

8

Suppressive effect of interleukin-4 neutralization differs for granulomas around Schistosoma mansoni eggs injected into mice compared with those around eggs laid in infected mice.

Eltoum IA, Wynn TA, Poindexter RW, Finkelman FD, Lewis FA, Sher A, Cheever AW. Eltoum IA, et al. Among authors: wynn ta. Infect Immun. 1995 Jul;63(7):2532-6. doi: 10.1128/iai.63.7.2532-2536.1995. Infect Immun. 1995. PMID: 7790066 Free PMC article.

9

Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology.

Wynn TA, Eltoum I, Oswald IP, Cheever AW, Sher A. Wynn TA, et al. J Exp Med. 1994 May 1;179(5):1551-61. doi: 10.1084/jem.179.5.1551. J Exp Med. 1994. PMID: 7909326 Free PMC article.

10

IL-12 inhibits Th2 cytokine responses induced by eggs of Schistosoma mansoni.

Oswald IP, Caspar P, Jankovic D, Wynn TA, Pearce EJ, Sher A. Oswald IP, et al. Among authors: wynn ta. J Immunol. 1994 Aug 15;153(4):1707-13. J Immunol. 1994. PMID: 7913944

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