Lear JD - Search Results

1

A helical-dipole model describes the single-channel current rectification of an uncharged peptide ion channel.

Kienker PK, DeGrado WF, Lear JD. Kienker PK, et al. Among authors: lear jd. Proc Natl Acad Sci U S A. 1994 May 24;91(11):4859-63. doi: 10.1073/pnas.91.11.4859. Proc Natl Acad Sci U S A. 1994. PMID: 7515180 Free PMC article.

2

Fluorescence studies of the secondary structure and orientation of a model ion channel peptide in phospholipid vesicles.

Chung LA, Lear JD, DeGrado WF. Chung LA, et al. Among authors: lear jd. Biochemistry. 1992 Jul 21;31(28):6608-16. doi: 10.1021/bi00143a035. Biochemistry. 1992. PMID: 1378757

3

Conformationally constrained alpha-helical peptide models for protein ion channels.

DeGrado WF, Lear JD. DeGrado WF, et al. Among authors: lear jd. Biopolymers. 1990 Jan;29(1):205-13. doi: 10.1002/bip.360290125. Biopolymers. 1990. PMID: 1691664

4

Synthetic amphiphilic peptide models for protein ion channels.

Lear JD, Wasserman ZR, DeGrado WF. Lear JD, et al. Science. 1988 May 27;240(4856):1177-81. doi: 10.1126/science.2453923. Science. 1988. PMID: 2453923

5

Charge selectivity of the designed uncharged peptide ion channel Ac-(LSSLLSL)3-CONH2.

Kienker PK, Lear JD. Kienker PK, et al. Among authors: lear jd. Biophys J. 1995 Apr;68(4):1347-58. doi: 10.1016/S0006-3495(95)80307-3. Biophys J. 1995. PMID: 7540427 Free PMC article.

6

Multiple oligomeric states regulate the DNA binding of helix-loop-helix peptides.

Fairman R, Beran-Steed RK, Anthony-Cahill SJ, Lear JD, Stafford WF 3rd, DeGrado WF, Benfield PA, Brenner SL. Fairman R, et al. Among authors: lear jd. Proc Natl Acad Sci U S A. 1993 Nov 15;90(22):10429-33. doi: 10.1073/pnas.90.22.10429. Proc Natl Acad Sci U S A. 1993. PMID: 8248126 Free PMC article.

7

A functionally defined model for the M2 proton channel of influenza A virus suggests a mechanism for its ion selectivity.

Pinto LH, Dieckmann GR, Gandhi CS, Papworth CG, Braman J, Shaughnessy MA, Lear JD, Lamb RA, DeGrado WF. Pinto LH, et al. Among authors: lear jd. Proc Natl Acad Sci U S A. 1997 Oct 14;94(21):11301-6. doi: 10.1073/pnas.94.21.11301. Proc Natl Acad Sci U S A. 1997. PMID: 9326604 Free PMC article.

8

Polar side chains drive the association of model transmembrane peptides.

Gratkowski H, Lear JD, DeGrado WF. Gratkowski H, et al. Among authors: lear jd. Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):880-5. doi: 10.1073/pnas.98.3.880. Proc Natl Acad Sci U S A. 2001. PMID: 11158564 Free PMC article.

9

Sequence determinants of the energetics of folding of a transmembrane four-helix-bundle protein.

Howard KP, Lear JD, DeGrado WF. Howard KP, et al. Among authors: lear jd. Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8568-72. doi: 10.1073/pnas.132266099. Proc Natl Acad Sci U S A. 2002. PMID: 12084917 Free PMC article.

10

Use of thiol-disulfide equilibria to measure the energetics of assembly of transmembrane helices in phospholipid bilayers.

Cristian L, Lear JD, DeGrado WF. Cristian L, et al. Among authors: lear jd. Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):14772-7. doi: 10.1073/pnas.2536751100. Epub 2003 Dec 1. Proc Natl Acad Sci U S A. 2003. PMID: 14657351 Free PMC article.

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