The docking of Arg2 of angiotensin II with Asp281 of AT1 receptor is essential for full agonism.
Feng YH, Noda K, Saad Y, Liu XP, Husain A, Karnik SS.
Feng YH, et al. Among authors: saad y.
J Biol Chem. 1995 May 26;270(21):12846-50. doi: 10.1074/jbc.270.21.12846.
J Biol Chem. 1995.
PMID: 7759541
Free article.
We showed earlier that Lys199 in transmembrane-helix-5 of the AT1 receptor binds the COOH-terminal alpha-carboxyl group of angiotensin II (Noda, K., Saad, Y., Kinoshita, A., Boyle, T. P., Graham, R. M., Husain, A., and Karnik, S. S. (1995) J. ...
We showed earlier that Lys199 in transmembrane-helix-5 of the AT1 receptor binds the COOH-terminal alpha-carboxyl group of angiotensin II (N …