Ejima A - Search Results

1

A new water-soluble camptothecin derivative, DX-8951f, exhibits potent antitumor activity against human tumors in vitro and in vivo.

Mitsui I, Kumazawa E, Hirota Y, Aonuma M, Sugimori M, Ohsuki S, Uoto K, Ejima A, Terasawa H, Sato K. Mitsui I, et al. Among authors: ejima a. Jpn J Cancer Res. 1995 Aug;86(8):776-82. doi: 10.1111/j.1349-7006.1995.tb02468.x. Jpn J Cancer Res. 1995. PMID: 7559102 Free PMC article.

2

Antitumor agents. V. Synthesis and antileukemic activity of E-ring-modified (RS)-camptothecin analogues.

Ejima A, Terasawa H, Sugimori M, Ohsuki S, Matsumoto K, Kawato Y, Yasuoka M, Tagawa H. Ejima A, et al. Chem Pharm Bull (Tokyo). 1992 Mar;40(3):683-8. doi: 10.1248/cpb.40.683. Chem Pharm Bull (Tokyo). 1992. PMID: 1611680

3

Antitumor agents. 7. Synthesis and antitumor activity of novel hexacyclic camptothecin analogues.

Sugimori M, Ejima A, Ohsuki S, Uoto K, Mitsui I, Matsumoto K, Kawato Y, Yasuoka M, Sato K, Tagawa H, et al. Sugimori M, et al. Among authors: ejima a. J Med Chem. 1994 Sep 16;37(19):3033-9. doi: 10.1021/jm00045a007. J Med Chem. 1994. PMID: 7932525

4

Synthesis and antitumor activity of ring A- and F-modified hexacyclic camptothecin analogues.

Sugimori M, Ejima A, Ohsuki S, Uoto K, Mitsui I, Kawato Y, Hirota Y, Sato K, Terasawa H. Sugimori M, et al. Among authors: ejima a. J Med Chem. 1998 Jun 18;41(13):2308-18. doi: 10.1021/jm970765q. J Med Chem. 1998. PMID: 9632364

5

Synthesis and antitumor activity of novel pyrimidinyl pyrazole derivatives.

Naito H, Sugimori M, Mitsui I, Nakamura Y, Iwahana M, Ishii M, Hirotani K, Kumazawa E, Ejima A. Naito H, et al. Among authors: ejima a. Chem Pharm Bull (Tokyo). 1999 Dec;47(12):1679-84. doi: 10.1248/cpb.47.1679. Chem Pharm Bull (Tokyo). 1999. PMID: 10748712

6

Growth inhibitory effect of a new camptothecin analog, DX-8951f, on various drug-resistant sublines including BCRP-mediated camptothecin derivative-resistant variants derived from the human lung cancer cell line PC-6.

Ishii M, Iwahana M, Mitsui I, Minami M, Imagawa S, Tohgo A, Ejima A. Ishii M, et al. Among authors: ejima a. Anticancer Drugs. 2000 Jun;11(5):353-62. doi: 10.1097/00001813-200006000-00005. Anticancer Drugs. 2000. PMID: 10912951

7

Synthesis and antitumor activity of novel pyrimidinyl pyrazole derivatives. II. Optimization of the phenylpiperazine moiety of 1-[5-methyl-1-(2-pyrimidinyl)-4-pyrazolyl]-3-phenylpiperazinyl-1-trans-propenes.

Naito H, Ohsuki S, Sugimori M, Atsumi R, Minami M, Nakamura Y, Ishii M, Hirotani K, Kumazawa E, Ejima A. Naito H, et al. Among authors: ejima a. Chem Pharm Bull (Tokyo). 2002 Apr;50(4):453-62. doi: 10.1248/cpb.50.453. Chem Pharm Bull (Tokyo). 2002. PMID: 11963990 Free article.

8

Synthesis and antitumor activity of novel pyrimidinyl pyrazole derivatives. III. Synthesis and antitumor activity of 3-phenylpiperazinyl-1-trans-propenes.

Naito H, Ohsuki S, Atsumi R, Minami M, Mochizuki M, Hirotani K, Kumazawa E, Ejima A. Naito H, et al. Among authors: ejima a. Chem Pharm Bull (Tokyo). 2005 Feb;53(2):153-63. doi: 10.1248/cpb.53.153. Chem Pharm Bull (Tokyo). 2005. PMID: 15684512 Free article.

9

Synthesis and antitumor activity of novel benzophenone derivatives.

Kumazawa E, Hirotani K, Burford SC, Kawagoe K, Miwa T, Mitsui I, Ejima A. Kumazawa E, et al. Among authors: ejima a. Chem Pharm Bull (Tokyo). 1997 Sep;45(9):1470-4. doi: 10.1248/cpb.45.1470. Chem Pharm Bull (Tokyo). 1997. PMID: 9331999

10

Synthesis and mechanism of action of novel pyrimidinyl pyrazole derivatives possessing antiproliferative activity.

Ohki H, Hirotani K, Naito H, Ohsuki S, Minami M, Ejima A, Koiso Y, Hashimoto Y. Ohki H, et al. Among authors: ejima a. Bioorg Med Chem Lett. 2002 Nov 4;12(21):3191-3. doi: 10.1016/s0960-894x(02)00568-1. Bioorg Med Chem Lett. 2002. PMID: 12372531

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