Kern ER - Search Results

1

Synthesis and antiproliferative and antiviral activity of 2'-deoxy-2'-fluoroarabinofuranosyl analogs of the nucleoside antibiotics toyocamycin and sangivamycin.

Krawczyk SH, Nassiri MR, Kucera LS, Kern ER, Ptak RG, Wotring LL, Drach JC, Townsend LB. Krawczyk SH, et al. Among authors: kern er. J Med Chem. 1995 Sep 29;38(20):4106-14. doi: 10.1021/jm00020a026. J Med Chem. 1995. PMID: 7562946

2

Structure-activity relationships of (S,Z)-2-aminopurine methylenecyclopropane analogues of nucleosides. Variation of purine-6 substituents and activity against herpesviruses and hepatitis B virus.

Chen X, Kern ER, Drach JC, Gullen E, Cheng YC, Zemlicka J. Chen X, et al. Among authors: kern er. J Med Chem. 2003 Apr 10;46(8):1531-7. doi: 10.1021/jm0205245. J Med Chem. 2003. PMID: 12672254

3

Synthesis and antiviral activity of (Z)- and (E)-2,2-[bis(hydroxymethyl)cyclopropylidene]methylpurines and -pyrimidines: second-generation methylenecyclopropane analogues of nucleosides.

Zhou S, Breitenbach JM, Borysko KZ, Drach JC, Kern ER, Gullen E, Cheng YC, Zemlicka J. Zhou S, et al. Among authors: kern er. J Med Chem. 2004 Jan 29;47(3):566-75. doi: 10.1021/jm030316s. J Med Chem. 2004. PMID: 14736238

4

(Z)- and (E)-[2-Fluoro-2-(hydroxymethyl)cyclopropylidene]methylpurines and -pyrimidines, a new class of methylenecyclopropane analogues of nucleosides: synthesis and antiviral activity.

Zhou S, Kern ER, Gullen E, Cheng YC, Drach JC, Matsumi S, Mitsuya H, Zemlicka J. Zhou S, et al. Among authors: kern er. J Med Chem. 2004 Dec 30;47(27):6964-72. doi: 10.1021/jm040093l. J Med Chem. 2004. PMID: 15615545

5

Nucleotides and pronucleotides of 2,2-bis(hydroxymethyl)methylenecyclopropane analogues of purine nucleosides: synthesis and antiviral activity.

Yan Z, Kern ER, Gullen E, Cheng YC, Drach JC, Zemlicka J. Yan Z, et al. Among authors: kern er. J Med Chem. 2005 Jan 13;48(1):91-9. doi: 10.1021/jm040149b. J Med Chem. 2005. PMID: 15634003

6

9-{[3-fluoro-2-(hydroxymethyl)cyclopropylidene]methyl}adenines and -guanines. Synthesis and antiviral activity of all stereoisomers1.

Zhou S, Kern ER, Gullen E, Cheng YC, Drach JC, Tamiya S, Mitsuya H, Zemlicka J. Zhou S, et al. Among authors: kern er. J Med Chem. 2006 Oct 5;49(20):6120-8. doi: 10.1021/jm0607404. J Med Chem. 2006. PMID: 17004726 Free PMC article.

7

Improved synthesis and biological evaluation of an acyclic thiosangivamycin active against human cytomegalovirus.

Renau TE, Nassiri MR, Swayze EE, Kern ER, Townsend LB, Drach JC. Renau TE, et al. Among authors: kern er. Antiviral Res. 1992 Jul 1;19(1):15-28. doi: 10.1016/0166-3542(92)90053-8. Antiviral Res. 1992. PMID: 1332597 Free article.

8

Synthesis, antiproliferative, and antiviral activity of certain 4-substituted and 4,5-disubstituted 7-[(1,3-dihydroxy-2-propoxy)methyl]pyrrolo[2,3-d]pyrimidines.

Pudlo JS, Nassiri MR, Kern ER, Wotring LL, Drach JC, Townsend LB. Pudlo JS, et al. Among authors: kern er. J Med Chem. 1990 Jul;33(7):1984-92. doi: 10.1021/jm00169a028. J Med Chem. 1990. PMID: 2163454

9

Arabinofuranosylpyrrolo[2,3-d]pyrimidines as potential agents for human cytomegalovirus infections.

Krawczyk SH, Bernier-Rodriguez M, Nassiri MR, Kern ER, Wotring LL, Drach JC, Townsend LB. Krawczyk SH, et al. Among authors: kern er. J Med Chem. 1990 Dec;33(12):3160-9. doi: 10.1021/jm00174a011. J Med Chem. 1990. PMID: 2175356

10

(Z)- and (E)-2-((hydroxymethyl)cyclopropylidene)methyladenine and -guanine. New nucleoside analogues with a broad-spectrum antiviral activity.

Qiu YL, Ksebati MB, Ptak RG, Fan BY, Breitenbach JM, Lin JS, Cheng YC, Kern ER, Drach JC, Zemlicka J. Qiu YL, et al. Among authors: kern er. J Med Chem. 1998 Jan 1;41(1):10-23. doi: 10.1021/jm9705723. J Med Chem. 1998. PMID: 9438017

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