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Genotype, slow decrease in virus titer during interferon treatment and high degree of sequence variability of hypervariable region are indicative of poor response to interferon treatment in patients with chronic hepatitis type C.
Chayama K, Tsubota A, Arase Y, Saitoh S, Ikeda K, Matsumoto T, Hashimoto M, Kobayashi M, Kanda M, Morinaga T, et al. Chayama K, et al. Among authors: tsubota a. J Hepatol. 1995 Dec;23(6):648-53. doi: 10.1016/0168-8278(95)80029-8. J Hepatol. 1995. PMID: 8750162 Clinical Trial.
Pretreatment virus load and multiple amino acid substitutions in the interferon sensitivity-determining region predict the outcome of interferon treatment in patients with chronic genotype 1b hepatitis C virus infection.
Chayama K, Tsubota A, Kobayashi M, Okamoto K, Hashimoto M, Miyano Y, Koike H, Kobayashi M, Koida I, Arase Y, Saitoh S, Suzuki Y, Murashima N, Ikeda K, Kumada H. Chayama K, et al. Among authors: tsubota a. Hepatology. 1997 Mar;25(3):745-9. doi: 10.1002/hep.510250342. Hepatology. 1997. PMID: 9049229
[Cranial MRI in the patients with chronic liver disease (CLD)].
Nakamura T, Saitoh S, Ikeda K, Kobayashi M, Suzuki Y, Tsubota A, Koida I, Arase Y, Chayama K, Murashima N, Kumada H. Nakamura T, et al. Among authors: tsubota a. Nihon Shokakibyo Gakkai Zasshi. 1997 Mar;94(3):157-62. Nihon Shokakibyo Gakkai Zasshi. 1997. PMID: 9095633 Japanese.
317 results