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The p53 tumor suppressor targets a novel regulator of G protein signaling.
Buckbinder L, Velasco-Miguel S, Chen Y, Xu N, Talbott R, Gelbert L, Gao J, Seizinger BR, Gutkind JS, Kley N. Buckbinder L, et al. Proc Natl Acad Sci U S A. 1997 Jul 22;94(15):7868-72. doi: 10.1073/pnas.94.15.7868. Proc Natl Acad Sci U S A. 1997. PMID: 9223279 Free PMC article.
Endothelial protein kinase MAP4K4 promotes vascular inflammation and atherosclerosis.
Roth Flach RJ, Skoura A, Matevossian A, Danai LV, Zheng W, Cortes C, Bhattacharya SK, Aouadi M, Hagan N, Yawe JC, Vangala P, Menendez LG, Cooper MP, Fitzgibbons TP, Buckbinder L, Czech MP. Roth Flach RJ, et al. Among authors: buckbinder l. Nat Commun. 2015 Dec 21;6:8995. doi: 10.1038/ncomms9995. Nat Commun. 2015. PMID: 26688060 Free PMC article.
2-Aminopyridine-Based Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Inhibitors: Assessment of Mechanism-Based Safety.
Dow RL, Ammirati M, Bagley SW, Bhattacharya SK, Buckbinder L, Cortes C, El-Kattan AF, Ford K, Freeman GB, Guimarães CRW, Liu S, Niosi M, Skoura A, Tess D. Dow RL, et al. Among authors: buckbinder l. J Med Chem. 2018 Apr 12;61(7):3114-3125. doi: 10.1021/acs.jmedchem.8b00152. Epub 2018 Apr 3. J Med Chem. 2018. PMID: 29570292
Myeloperoxidase inhibition in mice alters atherosclerotic lesion composition.
Roth Flach RJ, Su C, Bollinger E, Cortes C, Robertson AW, Opsahl AC, Coskran TM, Maresca KP, Keliher EJ, Yates PD, Kim AM, Kalgutkar AS, Buckbinder L. Roth Flach RJ, et al. Among authors: buckbinder l. PLoS One. 2019 Mar 19;14(3):e0214150. doi: 10.1371/journal.pone.0214150. eCollection 2019. PLoS One. 2019. PMID: 30889221 Free PMC article.
46 results