Juvonen RO - Search Results

1

Molecular engineering of microsomal P450 2a-4 to a stable, water-soluble enzyme.

Sueyoshi T, Park LJ, Moore R, Juvonen RO, Negishi M. Sueyoshi T, et al. Among authors: juvonen ro. Arch Biochem Biophys. 1995 Sep 10;322(1):265-71. doi: 10.1006/abbi.1995.1461. Arch Biochem Biophys. 1995. PMID: 7574685

2

Roles of residues 129 and 209 in the alteration by cytochrome b5 of hydroxylase activities in mouse 2A P450S.

Juvonen RO, Iwasaki M, Negishi M. Juvonen RO, et al. Biochemistry. 1992 Nov 24;31(46):11519-23. doi: 10.1021/bi00161a033. Biochemistry. 1992. PMID: 1445886

3

Structural function of residue-209 in coumarin 7-hydroxylase (P450coh). Enzyme-kinetic studies and site-directed mutagenesis.

Juvonen RO, Iwasaki M, Negishi M. Juvonen RO, et al. J Biol Chem. 1991 Sep 5;266(25):16431-5. J Biol Chem. 1991. PMID: 1885576 Free article.

4

Structural alteration of mouse P450coh by mutation of glycine-207 to proline: spin equilibrium, enzyme kinetics, and heat sensitivity.

Juvonen RO, Iwasaki M, Sueyoshi T, Negishi M. Juvonen RO, et al. Biochem J. 1993 Aug 15;294 ( Pt 1)(Pt 1):31-4. doi: 10.1042/bj2940031. Biochem J. 1993. PMID: 8395817 Free PMC article.

5

Engineering mouse P450coh to a novel corticosterone 15 alpha-hydroxylase and modeling steroid-binding orientation in the substrate pocket.

Iwasaki M, Darden TA, Pedersen LG, Davis DG, Juvonen RO, Sueyoshi T, Negishi M. Iwasaki M, et al. Among authors: juvonen ro. J Biol Chem. 1993 Jan 15;268(2):759-62. J Biol Chem. 1993. PMID: 8419350 Free article.

6

Site-directed mutagenesis of mouse steroid 7 alpha-hydroxylase (cytochrome P-450(7) alpha): role of residue-209 in determining steroid-cytochrome P-450 interaction.

Iwasaki M, Lindberg RL, Juvonen RO, Negishi M. Iwasaki M, et al. Among authors: juvonen ro. Biochem J. 1993 Apr 15;291 ( Pt 2)(Pt 2):569-73. doi: 10.1042/bj2910569. Biochem J. 1993. PMID: 8484736 Free PMC article.

7

Structural flexibility and functional versatility of cytochrome P450 and rapid evolution.

Negishi M, Iwasaki M, Juvonen RO, Sueyoshi T, Darden TA, Pedersen LG. Negishi M, et al. Among authors: juvonen ro. Mutat Res. 1996 Feb 19;350(1):43-50. doi: 10.1016/0027-5107(95)00089-5. Mutat Res. 1996. PMID: 8657195

8

Alteration of the substrate specificity of mouse 2A P450s by the identity of residue-209: steroid-binding site and orientation.

Negishi M, Iwasaki M, Juvonen RO, Aida K. Negishi M, et al. Among authors: juvonen ro. J Steroid Biochem Mol Biol. 1992 Dec;43(8):1031-6. doi: 10.1016/0960-0760(92)90330-L. J Steroid Biochem Mol Biol. 1992. PMID: 22217847 Review.

9

Molecular characterization of the murine Coh locus: an amino acid difference at position 117 confers high and low coumarin 7-hydroxylase activity in P450coh.

Lindberg RL, Juvonen R, Negishi M. Lindberg RL, et al. Pharmacogenetics. 1992 Feb;2(1):32-7. doi: 10.1097/00008571-199202000-00006. Pharmacogenetics. 1992. PMID: 1302041

10

Alteration of high and low spin equilibrium by a single mutation of amino acid 209 in mouse cytochromes P450.

Iwasaki M, Juvonen R, Lindberg R, Negishi M. Iwasaki M, et al. J Biol Chem. 1991 Feb 25;266(6):3380-2. J Biol Chem. 1991. PMID: 1995602 Free article.

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