Negishi M - Search Results

1

Molecular engineering of microsomal P450 2a-4 to a stable, water-soluble enzyme.

Sueyoshi T, Park LJ, Moore R, Juvonen RO, Negishi M. Sueyoshi T, et al. Among authors: negishi m. Arch Biochem Biophys. 1995 Sep 10;322(1):265-71. doi: 10.1006/abbi.1995.1461. Arch Biochem Biophys. 1995. PMID: 7574685

2

Roles of residues 129 and 209 in the alteration by cytochrome b5 of hydroxylase activities in mouse 2A P450S.

Juvonen RO, Iwasaki M, Negishi M. Juvonen RO, et al. Among authors: negishi m. Biochemistry. 1992 Nov 24;31(46):11519-23. doi: 10.1021/bi00161a033. Biochemistry. 1992. PMID: 1445886

3

A DNA methylation site in the male-specific P450 (Cyp 2d-9) promoter and binding of the heteromeric transcription factor GABP.

Yokomori N, Kobayashi R, Moore R, Sueyoshi T, Negishi M. Yokomori N, et al. Among authors: negishi m. Mol Cell Biol. 1995 Oct;15(10):5355-62. doi: 10.1128/MCB.15.10.5355. Mol Cell Biol. 1995. PMID: 7565685 Free PMC article.

As shown with the Slp promoter (N. Yokomori, R. Moore, and M. Negishi, Proc. Natl. Acad. Sci. USA 92:1302-1306, 1995), the male-preferential demethylation also occurs at CpG/-97 in the Cyp 2d-9 promoter. ...

As shown with the Slp promoter (N. Yokomori, R. Moore, and M. Negishi, Proc. Natl. Acad. Sci. USA 92:1302-1306, 1995), the mal …

4

A nuclear factor (NF2d9) that binds to the male-specific P450 (Cyp 2d-9) gene in mouse liver.

Sueyoshi T, Kobayashi R, Nishio K, Aida K, Moore R, Wada T, Handa H, Negishi M. Sueyoshi T, et al. Among authors: negishi m. Mol Cell Biol. 1995 Aug;15(8):4158-66. doi: 10.1128/MCB.15.8.4158. Mol Cell Biol. 1995. PMID: 7623810 Free PMC article.

5

Structural alteration of mouse P450coh by mutation of glycine-207 to proline: spin equilibrium, enzyme kinetics, and heat sensitivity.

Juvonen RO, Iwasaki M, Sueyoshi T, Negishi M. Juvonen RO, et al. Among authors: negishi m. Biochem J. 1993 Aug 15;294 ( Pt 1)(Pt 1):31-4. doi: 10.1042/bj2940031. Biochem J. 1993. PMID: 8395817 Free PMC article.

6

Engineering mouse P450coh to a novel corticosterone 15 alpha-hydroxylase and modeling steroid-binding orientation in the substrate pocket.

Iwasaki M, Darden TA, Pedersen LG, Davis DG, Juvonen RO, Sueyoshi T, Negishi M. Iwasaki M, et al. Among authors: negishi m. J Biol Chem. 1993 Jan 15;268(2):759-62. J Biol Chem. 1993. PMID: 8419350 Free article.

7

Site-directed mutagenesis of mouse steroid 7 alpha-hydroxylase (cytochrome P-450(7) alpha): role of residue-209 in determining steroid-cytochrome P-450 interaction.

Iwasaki M, Lindberg RL, Juvonen RO, Negishi M. Iwasaki M, et al. Among authors: negishi m. Biochem J. 1993 Apr 15;291 ( Pt 2)(Pt 2):569-73. doi: 10.1042/bj2910569. Biochem J. 1993. PMID: 8484736 Free PMC article.

8

Structural flexibility and functional versatility of mammalian P450 enzymes.

Negishi M, Uno T, Darden TA, Sueyoshi T, Pedersen LG. Negishi M, et al. FASEB J. 1996 May;10(7):683-9. doi: 10.1096/fasebj.10.7.8635685. FASEB J. 1996. PMID: 8635685 Review.

9

Structural flexibility and functional versatility of cytochrome P450 and rapid evolution.

Negishi M, Iwasaki M, Juvonen RO, Sueyoshi T, Darden TA, Pedersen LG. Negishi M, et al. Mutat Res. 1996 Feb 19;350(1):43-50. doi: 10.1016/0027-5107(95)00089-5. Mutat Res. 1996. PMID: 8657195

10

The roles of individual amino acids in altering substrate specificity of the P450 2a4/2a5 enzymes.

Negishi M, Uno T, Honkakoski P, Sueyoshi T, Darden TA, Pedersen LP. Negishi M, et al. Biochimie. 1996;78(8-9):685-94. doi: 10.1016/s0300-9084(97)82525-4. Biochimie. 1996. PMID: 9010596 Review.

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