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Nanobody-based sensors reveal a high proportion of mGlu heterodimers in the brain.
Meng J, Xu C, Lafon PA, Roux S, Mathieu M, Zhou R, Scholler P, Blanc E, Becker JAJ, Le Merrer J, González-Maeso J, Chames P, Liu J, Pin JP, Rondard P. Meng J, et al. Among authors: blanc e. Nat Chem Biol. 2022 Aug;18(8):894-903. doi: 10.1038/s41589-022-01050-2. Epub 2022 Jun 9. Nat Chem Biol. 2022. PMID: 35681029 Free article.
Allosteric nanobodies uncover a role of hippocampal mGlu2 receptor homodimers in contextual fear consolidation.
Scholler P, Nevoltris D, de Bundel D, Bossi S, Moreno-Delgado D, Rovira X, Møller TC, El Moustaine D, Mathieu M, Blanc E, McLean H, Dupuis E, Mathis G, Trinquet E, Daniel H, Valjent E, Baty D, Chames P, Rondard P, Pin JP. Scholler P, et al. Among authors: blanc e. Nat Commun. 2017 Dec 6;8(1):1967. doi: 10.1038/s41467-017-01489-1. Nat Commun. 2017. PMID: 29213077 Free PMC article.
276 results